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Ultrasound for Neuropathic and Chronic Pain

This study is testing a non-invasive ultrasound device to see if it can reduce neuropathic (nerve-related) and chronic pain. The device uses focused ultrasound stimulation applied to the skin over a painful area, without surgery or medication. You might be able to join if you are an adult aged 18 or older, in good general health, and have chronic pain in certain nerve areas like the occipital, suprascapular, median, femoral/leg, stellate ganglion/vagus nerves. The main goal is to see how often any problems occur with the device. This study aims to find out if this ultrasound approach can safely and effectively reduce pain and if it's practical for future use.

Study design
This is an interventional study planning to enroll 90 participants. It compares active ultrasound stimulation to a sham (no treatment) device.
What's involved
You would participate in a single study visit, which includes stimulation sessions and pain assessments.
Compensation
Not stated in the trial record.
Follow-up
Your safety will be checked from the time of treatment until the next day (up to two days).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07572591

Ultrasound for Peripheral Nerve Modulation

Not Yet Recruiting
NAAges 18+Interventional
Stanford University
~90 participants
Updated 2026-05-07 on ClinicalTrials.gov
What's tested:UltrasoundSham (No Treatment)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of Device-Related Adverse Events
Measured over From treatment to the next day (up to two days)

Conditions

Neuropathic Pain
Chronic Pain

Explore related trials

Chronic PainNeuropathic Pain

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Sheng Xu, PhD · STUDY_DIRECTOR · Stanford University

Who to contact

Tom Park, PhD
[email protected]
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Exclusion

Patients with compromised skin integrity for whom device placement would result in increased risk of harm (such as those with extensive burns, active dermatologic conditions, or wounds that would prevent safe device placement)
Pregnant patients, as the devices have not been validated in this population
Additionally, the treating clinician may exclude any patient if they determine that study participation would be inappropriate for the patient's clinical condition.

What this trial measures

  • Incidence of Device-Related Adverse EventsFrom treatment to the next day (up to two days)

    Assessment of the number and severity of device- and procedure-related adverse events associated with focused ultrasound neuromodulation. Events will be graded according to standard clinical criteria, including pain, skin irritation, thermal effects, or neurologic symptoms.