Portable MRI for Pediatric Hypoxic Ischemic Brain Injury
This study is looking at a new way to detect brain injuries in children using a portable MRI (magnetic resonance imaging) machine. This special MRI machine can be brought right to a child's bedside in the intensive care unit (ICU), which is safer and easier than moving very sick children to a standard MRI. The study will compare the images from this portable MRI to images from regular MRIs or CT scans to see how well it finds acute (sudden) brain injuries caused by a lack of oxygen (hypoxic ischemic brain injury). We want to see if this portable MRI can accurately diagnose these injuries in children aged 0-17 years who are in the ICU and suspected of having this type of brain injury. The goal is to understand how this portable MRI can best be used in hospitals for children.
- Study design
- This is an interventional study planning to enroll 200 participants. It will compare the portable MRI to standard imaging methods.
- What's involved
- If you participate, your child will have a portable MRI at their bedside within 24 hours of a standard MRI or head CT. Any leftover blood or spinal fluid samples from routine clinical tests may also be collected.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome for this study is measured during intensive care admittance, with an average of 1 month.
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Portable MRI for Pediatric Hypoxic Ischemic Brain Injury
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jessica S Wallisch, MD · PRINCIPAL_INVESTIGATOR · Children's Mercy Kansas City
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Determine the sensitivity and specificity of pMRI for detection of acute pediatric focal ischemic brain injuries.During intensive care admittance, an average of 1 month
Perform pMRI on pediatric ICU patients within +/- 24 hours of a clinically obtained, conventional MRI. Compare detection rates and severity of ischemia and cerebral edema by pMRI vs conventional MRI to determine sensitivity and specificity.