This study is looking into whether wearing a special helmet that creates a static magnetic field can help reduce brain inflammation in adults with migraine. We are testing a device called a "static magnetic helmet." You might be able to join if you are between 18 and 65 years old and have been diagnosed with migraine by a doctor. The main goal is to see if the helmet changes a specific signal in your brain related to inflammation, which will be measured using special scans (PET-CT scans) before and after using the helmet. We will also ask you about your migraine symptoms. The study's current status is unclear, and it plans to enroll 10 participants.

Study design

This is a pilot study with 10 participants, designed to gather initial information about the effects of the magnetic helmet. It is not designed to determine if the treatment is effective for migraines.

What's involved

You would have three in-person visits to Massachusetts General Hospital over about 11 weeks. This includes screening tests, two PET-CT scans, and an MRI scan. You would also wear the magnetic helmet for 20 minutes daily for 21 days and complete daily migraine symptom surveys.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, Regional Brain [11C]PBR28 PET Signal, is measured from the pre-intervention scan to the post-intervention scan, approximately 21 days later.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.