NCT07585474

Gut Microbiome Response to Long-Haul Travel in Elite Football Players

Enrolling by Invitation
NAAges 18–40Interventional
Sheffield Hallam University
~30 participants
Updated 2026-05-13 on ClinicalTrials.gov
What's tested:Probiotic CapsulePlacebo

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Gut Microbiome
Measured over 3-4 weeks
Microbial Composition
Immune Function
2 sites across 2 states
Tennessee1
West Midlands1
  • George Davis, Masters · PRINCIPAL_INVESTIGATOR · Sheffield Hallam University

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Male professional footballers who are involved in regular training during the pre-season period.
Generally healthy, with no acute or chronic illnesses that could interfere with the study intervention or outcomes.
Not currently consuming probiotics, prebiotics, or antibiotics within 4 weeks prior to enrolment.
Willing to refrain from starting any new dietary supplements or probiotics during the study period.
Able and willing to provide written informed consent.

Exclusion

History of gastrointestinal disorders (e.g., Crohn's disease, ulcerative colitis, irritable bowel syndrome) or chronic diseases that could interfere with probiotic metabolism or study outcomes.
Acute illness (e.g., infection) within 2 weeks prior to enrollment.
Known allergy or hypersensitivity to components of the probiotic or placebo. - - - Use of antibiotics, probiotics, prebiotics, or synbiotics within 4 weeks prior to study start.
Use of immunosuppressive medications or other supplements likely to impact gut microbiota.
Regular use of alcohol or drugs at levels that could interfere with study participation or outcomes.
Participation in another clinical trial within the past 3 months.
Any injury or medical condition that limits participation in full training or matches during the study period.
  • Gut Microbiome3-4 weeks

    The gut microbiome is the complex community of microorganisms in the gastrointestinal tract that plays a vital role in digestion, immune regulation, and overall physiological resilience. In elite athletes, long-haul travel and pre-season training in hot environments can place additional stress on the gastrointestinal system, potentially leading to dysbiosis, gastrointestinal discomfort, and impaired performance or recovery.