This study, called VISION-INOCA, is looking at people with Ischemia and Non-obstructive Coronary Arteries (INOCA). This means you have symptoms of heart-related chest pain, but your main heart arteries are not blocked. Researchers want to understand how inflammation in your blood vessels (vascular endothelial profiles) is connected to your symptoms and how well you can do daily activities. You would undergo standard procedures like invasive coronary angiography and coronary function testing. Researchers will also collect endothelial cells from your coronary arteries and wear a Fitbit to track your physical activity and sleep. The study will measure changes in your angina (chest pain) and activity levels using questionnaires at the beginning and after one year. This study is open to adults aged 18 and older who are referred for a clinically indicated coronary angiography and have suspected INOCA.

Study design

This is an observational study planning to enroll 250 participants. It is not a drug trial, but rather aims to understand the connections between vascular inflammation and health in INOCA.

What's involved

You would undergo invasive coronary angiography and coronary function testing as part of your standard medical care. Endothelial cells would be collected, and you would wear a Fitbit device. You would also complete questionnaires at the start of the study and again after one year.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for one year, with assessments at baseline and at the one-year mark.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.