Observational Study on Chemotherapy Response in Gastric Cancer
This study is looking at how well people with stage II or III gastric (stomach) cancer respond to standard 5-FU-based adjuvant chemotherapy after surgery. Researchers are analyzing genetic information from tumor tissue to create a model that can predict who will benefit most from this treatment. The goal is to better understand why some patients respond well and others don't, which could help doctors make more informed decisions about your care. To join, you must have stage II or III gastric cancer, have had surgery, received 5-FU-based chemotherapy, and have tumor tissue available for analysis. The study is trying to enroll 329 participants, but its current status is unclear. Success for this study means developing a model that can accurately predict treatment response based on whether cancer returns within three years after surgery.
- Study design
- This is an observational study, meaning no new treatments are given. Researchers are studying existing patient data and tissue samples.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants' treatment response will be measured at 3 years after surgery to see if their cancer has returned.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Treatment response based on 3-year recurrence-free survival3 years after surgery
Treatment response was defined based on recurrence-free survival (RFS). Patients who developed recurrence within 3 years after curative surgery were classified as non-responders, whereas those without recurrence were classified as responders.