Study of Aritinercept for Generalized Myasthenia Gravis

This study is testing a drug called aritinercept in people with generalized myasthenia gravis (gMG), a condition that causes muscle weakness. Researchers want to see how safe aritinercept is and if your body tolerates it well. They will also look at how the drug works in your body and if it helps with gMG symptoms. You may receive aritinercept or a placebo (an inactive substance). The study is open to adults aged 18 to 85 who have gMG classified as MGFA Class II-IV. You cannot join if you have had cancer recently or are pregnant or breastfeeding. The study plans to enroll 81 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 81 participants with generalized myasthenia gravis, who will receive either aritinercept or a placebo via subcutaneous injection.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will assess safety and tolerability from the start of the study until its completion, which could be up to 73 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07596901

Study of Aritinercept in Patients With Generalized Myasthenia Gravis

Recruiting
PHASE1Ages 18–85InterventionalTreatment
Aurinia Pharmaceuticals Inc.
~81 participants
Updated 2026-08-03 on ClinicalTrials.gov
What's tested:AritinerceptPlacebo

At a glance

Recruiting sites
11 of 11 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To assess the safety and tolerability of aritinercept: Incidence of treatment-emergent adverse events
Measured over Baseline to study completion, up to 73 weeks
Myasthenia Gravis, Generalized
11 sites across 5 states
Florida5
Illinois2
Michigan2
California1
Texas1
Aurinia Clinical Trials Information
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Eligibility criteria

Inclusion

Adult patients (18-85 years old)
Myasthenia Gravis Foundation of America (MGFA) Class II-IV gMG

Exclusion

Current or medical history of malignancy within the last 5 years
Pregnant, breastfeeding or intending to become pregnant during the Study
  • To assess the safety and tolerability of aritinercept: Incidence of treatment-emergent adverse eventsBaseline to study completion, up to 73 weeks