This study is testing if a medication called tirzepatide can help people quit smoking. Tirzepatide is given as an injection under the skin. You might be able to join if you are between 21 and 65 years old, smoke at least 10 cigarettes a day, have been smoking for over 2 years, and have a body mass index (BMI) of 25 kg/m2 or higher (meaning you are overweight or have obesity). The study will look at how many people can stop smoking for at least 7 days, both during treatment and 6 months later. The current recruitment status for this study is unclear.

Study design

This is a placebo-controlled study, meaning some participants will receive tirzepatide and others will receive a saline injection (placebo). It plans to enroll 300 participants across four different locations.

What's involved

Participants will attend weekly clinic visits for 16 weeks to receive injections, followed by additional follow-up visits at Week 17 and Week 27.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed up to 6 months after their target quit date, with a final assessment at Week 27.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.