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Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial

This study is looking at whether a special computer tool, called an EHR-Embedded AKI Risk Score, can help doctors prevent acute kidney injury (AKI) after surgery. AKI is a sudden decrease in kidney function. The tool uses information from your electronic health record (EHR) to predict your risk of AKI before surgery. Doctors will either see this risk score alone, or see it with an alert that suggests best practices for kidney protection. The study is for adults aged 18 and older who are having non-obstetric surgery at UCSF and are expected to stay overnight. We will measure changes in your creatinine levels (a marker of kidney function) from before surgery to 1-2 days after surgery to see if the tool helps. The study aims to enroll 25,518 participants, but its current status is unclear.

Study design
This is an interventional study where attending anesthesiologists are randomly assigned to one of three groups: control (risk score hidden), score only, or score plus an advisory. This study plans to include 25,518 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your kidney function will be checked from before surgery to 1-2 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07604662

Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial

Not Yet Recruiting
NAAges 18+InterventionalScreening
University of California, San Francisco
~25,518 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:EHR-Embedded AKI Risk ScoreEHR-Embedded AKI Risk Score with Best Practice Advisory

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Post-operative Change in Creatinine
Measured over From pre-operative baseline to 1-2 days post-operative level

Conditions

Acute Kidney Injury
Surgery Complications
Anesthesia

Explore related trials

Acute Renal Failure

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Andrew Bishara, MD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

Who to contact

Andrew Bishara, MD
[email protected]
415-502-5880
Email the study team

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Eligibility criteria

Inclusion

Adults ≥18 years undergoing non-obstetric surgery at UCSF.
Inpatient cases with expected overnight stay.
Baseline eGFR ≥15 mL/min/1.73 m².
Managed by an attending anesthesiologist randomized to one of three arms (CRNAs/residents follow attending).
Data available in the UCSF EHR for risk scoring and outcomes.

Exclusion

Obstetric procedures.
Chronic dialysis patients.
Kidney transplant recipients.
Cases without baseline creatinine/eGFR or missing essential EHR elements needed for scoring/outcomes (operational exclusions).
Outpatient procedures without expected overnight stay.

What this trial measures

  • Post-operative Change in CreatinineFrom pre-operative baseline to 1-2 days post-operative level

    Maximum continuous change in serum creatinine (mg/dL) from baseline to post-operative day 1-2