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Understanding Brain Activity During Decision-Making in Epilepsy Patients

This observational study is looking at how the brain makes decisions in adult epilepsy patients who are already undergoing monitoring for seizures. You would play a simple decision-making game where you identify the source of a sound. While you play, researchers will track your eye movements and record your brain activity using electrodes already in place for your epilepsy monitoring. The goal is to understand how your brain works during these tasks and how your decisions are made. Researchers will look at changes in your pupil size, your responses in the game, and your brain activity. The study aims to enroll 30 participants and its current status is unclear.

Study design
This is an observational study involving 30 participants. It is not a drug trial, but rather looks at brain activity and behavior.
What's involved
You would participate in one session of a decision-making game, lasting approximately 30 minutes, while eye-tracking and intracranial electrode recordings are taken.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07606469

Human Neural Correlates of Multi-Timescale Inference

Not Yet Recruiting
Not specifiedAges 18+Observational
University of Colorado, Boulder
~30 participants
Updated 2026-05-26 on ClinicalTrials.gov
What's tested:Decision-making taskeye tracking

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pupil size changes with respect to task features
Measured over continuous recording during task, up to 30 minutes
+2 more outcomes measured

Conditions

Cognition
Brain Activity

Explore related trials

Seizure Disorder

Where it's being run

1 sites across 1 states
Colorado1

Who to contact

Tahra Eissa
[email protected]
(303) 492-6974
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Epilepsy patients undergoing intracranial electrode monitoring for uncontrolled seizures.
no lesions identified in the participants' brains
capable of giving consent

Exclusion

seizure activity during task recording
electrodes in regions of interest are identified to be the seizure focus
task performance outside of the normal range as determined from online studies with healthy participants

What this trial measures

  • Pupil size changes with respect to task featurescontinuous recording during task, up to 30 minutes

    pupil size will be measured with a portable eye-tracking device and correlated with task features

  • Behavioral ResponsesApproximately 10 seconds per trial, up to 30 minutes total

    Patient selects one of two choices on each trial using the computer keyboard

  • Intracranial electrode recordings to measure changes in brain activity during decision makingduration of the task, approximately 30 minutes

    Intracranial neural recordings from patients who are implanted with electrodes for clinical purposes tha take place during the decision-making task