Back to search results

Physiatry-Led Cancer Prehabilitation for Gynecologic Cancer

This study is looking at whether a program led by a physiatrist (a doctor specializing in physical medicine and rehabilitation) can help improve physical function in women with stage III-IVA gynecologic cancer. This program, called prehabilitation, happens during your systemic treatment (like chemotherapy) before surgery. Many women with gynecologic cancer face challenges like extreme tiredness and other physical issues. This study aims to see if starting supportive care before surgery can help you feel better and have better outcomes. You would receive educational materials, set goals, and attend a cancer physiatry consultation. The study plans to enroll 25 participants and is currently unclear on its recruitment status. Success for this study means that most participants complete and stick to the training program.

Study design
This is an interventional study with a planned enrollment of 25 participants. It is not specified if it is randomized or blinded.
What's involved
You would need to comply with a physiatry consultation, start a tailored training program, and attend follow-up assessments. The primary goal is to see if you adhere to the training program for up to 28 days immediately prior to surgery.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures feasibility up to 28 days immediately prior to surgery. Longer-term follow-up is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07608445

Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients

Not Yet Recruiting
NAAges 18+InterventionalSupportive care
City of Hope Medical Center
~25 participants
Updated 2026-05-27 on ClinicalTrials.gov
What's tested:Educational InterventionGoal SettingInterviewReferralRehabilitationSupportive Care

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Participant completion and adherence to the prescribed training program (Feasibility)
Measured over Up to 28 days immediately prior to surgery

Conditions

Malignant Female Reproductive System Neoplasm

Explore related trials

Malignant Female Reproductive System Neoplasm

Where it's being run

2 sites across 1 states
California2

Study leadership

  • Jessica Cheng · PRINCIPAL_INVESTIGATOR · City of Hope Medical Center

Who to contact

Jessica Cheng
[email protected]
626-218-4673
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

PATIENT: Documented informed consent of the participant
PATIENT: Willingness to comply with a physiatry consultation, start a tailored training program, and follow-up assessments
PATIENT: Age: ≥ 18 years
PATIENT: Able to read and write in English
PATIENT: A diagnosis of stage III-IVA gynecologic cancer planned for NST
PATIENT: Plan to start NST at City of Hope Orange County
HEALTHCARE TEAM: Documented informed consent of the participant
HEALTHCARE TEAM: Willingness to complete the Healthcare Worker Survey
HEALTHCARE TEAM: ≥ 18 years old
HEALTHCARE TEAM: Physicians, advanced practice providers, nurses, medical assistants, rehabilitation therapists, social workers, dietitians, mental health professionals, and other clinical staff who interact with study participants in the course of routine care

Exclusion

PATIENT: Current or planned cancer treatment for a second cancer
PATIENT: Clinically significant uncontrolled illness limiting participation with the research intervention and assessments
PATIENT: Stage IVB cancer with distant metastases
PATIENT: Other active malignancy
PATIENT: Pregnant or breastfeeding
PATIENT: Any other condition that would, in the Investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures
PATIENT: Meeting or exceeding exercise guidelines over the last one month based on the responses from the Godin-Shephard Leisure Time Physical Activity Questionnaire (GSLTPAQ)
PATIENT: Started second cycle before the physiatry consult
PATIENT: Inability to independently follow instructions for study assessments for any reason such as mental incapacitation or significant emotional or psychological disorder that, in the opinion of the investigators, precludes study entry. (These patients may not be able to cooperate with the prehabilitation interventions or with the data collection process.)
PATIENT: Unable to independently answer questionnaires in English
HEALTHCARE TEAM: Healthcare workers who do not interact with study participants and therefore cannot provide relevant feedback

What this trial measures

  • Participant completion and adherence to the prescribed training program (Feasibility)Up to 28 days immediately prior to surgery

    Feasibility will be determined primarily by participant adherence to the prescribed training program during the 28-day period immediately prior to surgery, with the goal of \> 70% adherence across each key category-exercise (aerobic and resistance), nutrition, and mind/spirit practice-in \> 70% of enrolled patients. Adherence will be measured via a self-reported weekly training log that will be turned in routinely to the clinical research staff. Feasibility assessment will include descriptive statistics such as frequencies (%), along with estimates of precision (95% confidence intervals).