NCT07610473
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
Recruiting
PHASE2Ages 18–75InterventionalTreatmentDraig Therapeutics Ltd
~118 participants
Updated 2026-08-12 on ClinicalTrials.gov
What's tested:DT-101Placebo
At a glance
Recruiting sites
22 of 22 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in total Montgomery Åsberg depression rating scale (MADRS) score, at Day 56
Measured over from enrolment to day 56
Conditions
Where it's being run
22 sites across 12 statesFlorida5
California3
Illinois2
New York2
Pennsylvania2
Texas2
Arizona1
Arkansas1
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
The participant is able to read, understand and communicate in the local language used at the study site, and is willing to provide written informed consent
Male or female (assigned at birth, inclusive of all gender identities) participant must be 18 to 75 years of age, inclusive at the time of signing the informed consent.
Has recurrent depression (defined as at least one prior episode excluding the current one), as diagnosed by DSM 5-TR (Diagnostic and Statistical Manual of Mental Disorders, 2022).
Exclusion
Pregnant or breastfeeding or plans to become pregnant during the study.
Unstable medical condition or unstable chronic disease.
Significant neurological abnormality.
History of moderate or severe alcohol or drug use disorder as per DSM-5-TR in the 6 months prior to Screening.
History of seizure.
In the investigator's opinion, the participant is not capable of adhering to the protocol requirements.
What this trial measures
- Change from baseline in total Montgomery Åsberg depression rating scale (MADRS) score, at Day 56from enrolment to day 56