Wearable Biosensor Patch for Post-Surgery Monitoring

This study is testing a wearable biosensor patch for patients having abdominal or chest surgery. The patch aims to non-invasively monitor important substances that are usually checked with blood tests, potentially reducing the need for frequent blood draws. It uses gentle electrical stimulation to collect sweat and then measures things like glucose and inflammation markers. The main goal is to see if collecting sweat with the patch is practical and safe. You may be able to join if you are at least 18 years old, scheduled for an abdominal or chest surgery with at least a 3-day hospital stay, and willing to provide sweat samples and complete surveys. The study is currently unclear on its recruitment status and plans to enroll 20 participants.

Study design
This is an interventional study with 20 planned participants, testing a wearable biosensor patch.
What's involved
You would wear a biosensor patch during surgery, and then wear another patch on your wrist for 2-4 hours, up to twice daily, for up to 3 days after surgery. You will also provide sweat samples, complete surveys, and allow review of your medical records.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, successful sweat collections, is measured for up to 1 year.

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NCT07612085

A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery

Not Yet Recruiting
NAAges 18+InterventionalDiagnostic
City of Hope Medical Center
~20 participants
Updated 2026-05-28 on ClinicalTrials.gov
What's tested:Biospecimen CollectionElectronic Health Record ReviewInterviewSurvey AdministrationWearable Biosensor Patch

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of successful sweat collections (feasibility)
Measured over Up to 1 year
Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm
1 sites across 1 states
California1
  • Kelly Mahuron · PRINCIPAL_INVESTIGATOR · City of Hope Medical Center

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Eligibility criteria

Inclusion

Age ≥ 18 years
Scheduled to have an elective abdominal or thoracic operation with anticipated post-operative hospitalization ≥ 3 days
Willingness to provide sweat samples, complete surveys, and permit review of medical records for research use
Ability to consent to the study procedures

Exclusion

Carbachol or pilocarpine allergy
Adhesive/tape allergy
Damaged or irritated skin on one or both wrists that prohibits placement of the biosensor and sweat collecting devices
Pregnant women
Children less than 18 years of age
  • Proportion of successful sweat collections (feasibility)Up to 1 year

    A successful collection will be defined by patch application with data successfully recorded and sent to the database. Examples of failed collections include, but are not limited to, a patch falling off before data collection can occur or a patch failing to collect and send data to the database. The number of successful collections will be reported as a proportion of the total number of attempted applications. All analyses will be descriptive. Unless otherwise specified, continuous variables will be summarized with mean, standard deviation, median, interquartile range, minimum, and maximum; categorical variables with counts and percentages. Given the small sample, two-sided 95 percent exact (Clopper-Pearson) confidence intervals will be provided for proportions. In addition to the overall success rate, the success rates for each type of patch (intraoperative and postoperative) will be described. All causes of failure (including unknown causes) will be reported.