{ "Observational Study for Metastatic HER2+ or Triple Negative Breast Cancer", "This study aims to understand why breast cancer spreads to the brain. Researchers want to collect samples of spinal fluid (CSF), blood, tumor tissue, and saliva from people with metastatic HER2-positive (HER2+) or triple negative breast cancer (TNBC). You can join if your cancer has spread to other parts of your body, but not to your brain. The goal is to see if tumor DNA in these samples can help predict when the cancer might spread to the brain. This information could help doctors identify people at high risk and potentially prevent brain metastases in the future. You will need to be able to have a lumbar puncture (spinal tap) and a brain MRI.", "design": "This is an observational study that plans to enroll 139 participants. It is a single-site study focused on collecting samples for analysis.", "commitments": "You will be screened, have blood tests to check kidney function, and undergo a lumbar puncture and brain MRI. Samples of CSF, blood, tumor tissue, and saliva or buccal mucosa will be collected at the start of the study and possibly later.", "compensation": "Not stated in the trial record.", "follow_up": "The primary goal is the collection of CSF samples, measured for up to 3 years.", }

Study design

Not specified.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.