Fasting Intervention for Endometrial Cancer

This study is looking at whether it is safe for women with endometrial cancer to fast (not eat) overnight before their surgery. Doctors believe that problems with metabolism, like high blood sugar, can make cancer grow or make treatments less effective. Early research suggests that fasting overnight might help improve these issues. You may be able to join if you are a woman aged 18 or older with Type I (low-grade) endometrial cancer that has been confirmed, and you are planning to have a minimally invasive hysterectomy. The study aims to see how many people are willing to join and complete the fasting, and if they are satisfied with it. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 42 participants. The study does not specify a phase.
What's involved
You would be asked to follow a Prolonged Overnight Fasting (POF) schedule, gradually increasing your nightly fast to 14 hours. You will also have blood samples collected at three different times and wear a blood sugar monitor on your arm for most of the study duration.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 10 weeks to assess adherence and satisfaction with the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07622901

Fasting InTervention for Endometrial Cancer

Recruiting
NAAges 18+InterventionalSupportive care
University of Miami
~42 participants
Updated 2026-07-14 on ClinicalTrials.gov
What's tested:Prolonged Overnight Fasting (POF)Blood Specimen CollectionBlood Sugar MonitorHysterectomy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of Recruitment: Percentage of Participants That Consent to Participate and Meet Eligibility Criteria
Measured over Baseline
+2 more outcomes measured
Endometrial Cancer
1 sites across 1 states
Florida1
  • Tracy E Crane, PhD, RDN · PRINCIPAL_INVESTIGATOR · University of Miami

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  • Feasibility of Recruitment: Percentage of Participants That Consent to Participate and Meet Eligibility CriteriaBaseline

    Feasibility of recruitment will reported as the percentage of participants who consent to participate and meet eligibility criteria. Criterion for success: At least (≥) 50% of all eligible participants at Baseline (T0) consent to participate between both arms.

  • Feasibility of Retention: Percentage of Participants Who Adhere to and Complete the Intervention and Data Collection at All Time Points.Up to 10 weeks

    Feasibility of retention will be reported as the percentage of participants who adhere to and complete the prolonged overnight fasting (POF) intervention and data collection at all time points. Criterion for success: Greater than (\>) 70% of all assigned participants complete the intervention and data collection at all time points (T2).

  • Acceptability: Percentage of Participants Who Report Satisfaction with the Intervention.Up to 10 weeks

    Acceptability will be reported as the percentage of participants who report satisfaction with the prolonged overnight fasting (POF) intervention after completion. Criterion for success: Greater than (\>) 80% of all assigned participants report satisfaction with the intervention at the time of study completion (T2).