Stanford University Microbiome Bank

This study, called the Stanford University Microbiome Bank, is looking for healthy adults to donate stool samples. It's an observational study, meaning there are no interventions or treatments being tested on you. Instead, researchers want to collect and understand your microbiome (the community of tiny organisms living in your gut), as well as your metabolic, immune, and dietary profiles. This information will help them learn more about how the gut microbiome affects health and disease, and support the development of new therapies. The main goal is to see how many potential donors meet the eligibility requirements. You can join if you are between 18 and 80 years old, in good general health, and can travel to the donation facility weekly.

Study design: This is an observational study with a planned enrollment of 50 healthy adult participants. It is not testing any specific drug or treatment.
What's involved: You would provide stool samples weekly or monthly for up to 12 months, along with blood and saliva samples. You would also swallow a capsule (CapScan) to collect intestinal fluid.
Compensation: Not stated in the trial record.
Follow-up: Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Stanford University Microbiome Bank

Not Yet Recruiting

Not specifiedAges 18–80Observational

Sean Spencer

~50 participants

Updated 2026-06-04 on ClinicalTrials.gov

What's tested:Microbiome bank

At a glance

Recruiting sites

0 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Donor Eligibility Rate

Measured over During screening period

Conditions

Healthy Adult Participants

NCT07625059

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

Stanford University
Palo Alto, Californiastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

Sean Spencer, MD, PhD · PRINCIPAL_INVESTIGATOR · Stanford University

Who to contact

Roujheen Sabetan, MPH

[email protected]

650-498-8188

Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime

Eligibility criteria

Inclusion

Provision of signed and dated informed consent form

Stated willingness to comply with all study procedures and availability for the duration of the study

Any person aged 18-80 years of age, inclusive at the time of signing the consent

In good general health as evidenced by medical history

Ability to travel to donation facility on a weekly basis

Residence within 5 miles of Stanford Campus

For females of reproductive potential: use of highly effective contraception for at least 1 month prior to screening and agreement to use such a method during study participation

Capable of providing signed informed consent.

Exclusion

Inflammatory bowel disease

Enteric infections

Previous infection with Clostridium difficile

History of gastrointestinal surgery: Participants with gastrointestinal surgeries below the pylorus will be excluded from this protocol, including participants with a history of colectomy, segmental colonic resection, and small bowel resections.

Documented severe gastroparesis

Active intestinal obstruction

Dysphagia (oropharyngeal, esophageal, functional or neuromuscular)

History or current malignancy diagnosis

History of recurrent aspiration episodes

Any conditions associated with a high risk of bleeding, including but not limited to coagulopathy/bleeding disorder, severe liver disease, active or recent GI bleeding, or recent abdominal or other GI surgery

Active diagnosis of major depressive disorder

Active diagnosis of major anxiety disorder

Severe immunodeficiency, inherited or acquired (e.g., Human immunodeficiency virus, active chemotherapy or immunosuppressive medications \[including steroids, biologic therapy, or bone marrow suppressive agents\], or radiation therapy)

BMI of less than 18 or BMI greater than 30

Record of eating disorders

Active use of GLP-1 inhibitors

Diagnosis of Human immunodeficiency virus infection; Hepatitis A, B, C \& E; Epstein Bar Virus; parasitic infections; Syphilis

Pregnancy \& lactation

Active drug, or alcohol use disorder

Tobacco, marijuana and e-cigarette use

Any other significant medical condition that could confound or interfere with evaluation of safety or tolerability or prevent compliance with the study protocol at the discretion of the Investigator

Active antibiotic use

Active treatment with high levels of immunosuppressive therapies (active chemotherapy or immunosuppressive medications \[including steroids, biologic therapy, or bone marrow suppressive agent\], or radiation therapy)

Simultaneous participation in another interventional clinical trial

Inability to comply with research requirements

What this trial measures

Donor Eligibility RateDuring screening period
Proportion of screened individuals who meet eligibility criteria for stool donation

Trialytics