DB-3Q for Medically Refractory Crohn's Disease

This study is looking into DB-3Q as a potential treatment for Crohn's disease that hasn't responded well to other therapies. DB-3Q is a product made from bone marrow stem cells. Researchers want to see if DB-3Q is safe and effective compared to a placebo (a salt water solution). You might be able to join if you are 18-75 years old and have Crohn's disease for at least six months that hasn't improved with at least one advanced immune therapy. The main goal is to see how much your Crohn's disease symptoms improve after 12 weeks, measured by a score called SES-CD. The current status of this study is unclear, and it plans to enroll 36 participants.

Study design
This study is an interventional trial comparing DB-3Q to a placebo. It plans to enroll 36 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 12 weeks, suggesting follow-up for at least that long.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07625293

DB-3Q for the Treatment of Medically Refractory Crohn's Disease

Not Yet Recruiting
PHASE2Ages 18–75InterventionalTreatment
Direct Biologics, LLC
~36 participants
Updated 2026-06-12 on ClinicalTrials.gov
What's tested:DB-3QPlacebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in SES-CD Score
Measured over 12 Weeks
Crohn Disease (CD)
1 sites across 1 states
Missouri1

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  • Change from baseline in SES-CD Score12 Weeks

    Simple Endoscopic Score for Crohn's Disease (SES-CD) is a standardized tool used by gastroenterologists to assess and quantify the severity of Crohn's disease during an endoscopy or colonoscopy. The scale goes from 0 to greater than 15, with a lower score being better.