Smart Discharges for Older Children with Sepsis

This observational study, called "Smart Discharges for Older Children," is looking at children aged 5 to 16 years in East Africa who are admitted to the hospital with a proven or suspected infection like sepsis (a life-threatening response to infection). The goal is to create tools that can identify which children are at highest risk of dying after they go home from the hospital. Currently, about 5% of children discharged after sepsis hospitalization in low- and middle-income countries die in the weeks following discharge. This study will follow 4000 children to understand how to better predict and prevent these deaths, ultimately aiming to improve their health outcomes after leaving the hospital.

Study design
This is an observational study, meaning researchers will watch and collect information without giving any specific intervention. It plans to enroll 4000 participants.
What's involved
You would need to provide contact information for phone or in-person follow-up after discharge.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed from discharge until 6 months post-discharge to track deaths.

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NCT07629154

Smart Discharges for Older Children

Recruiting
Not specifiedAges 5–16Observational
University of British Columbia
~4,000 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:No Intervention: Observational Cohort

At a glance

Recruiting sites
2 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of children who die post-discharge
Measured over Discharge until 6 months post-discharge
Sepsis
7 sites across 7 states
California1
New York1
Washington1
British Columbia1
Rwanda1
Tanzania1
Uganda1

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Eligibility criteria

Inclusion

Age between 0 and 16 years admitted to pediatric ward of hospital for proven or suspected infection
Provide informed consent
Ability to provide contact information (phone number or address) for phone or in-person follow-up

Exclusion

Child lives outside of the catchment area of a study site
Admitted for elective procedures, trauma, or short-term observation
Language barriers
  • Number of children who die post-dischargeDischarge until 6 months post-discharge