Optimizing Heart Imaging for Women with Early-Stage Breast Cancer

This study is looking at ways to reduce the number of heart imaging tests (like echocardiograms) for women with early-stage breast cancer who are receiving HER2-targeted therapy. The goal is to see if a personalized approach can safely lower unnecessary tests while still catching any heart problems early. You may be able to join if you are a woman between 18 and 79 years old with HER2-positive breast cancer and a healthy heart function (LVEF ≥ 55%) before treatment. The study will measure how many imaging tests are done and how long it takes to complete your HER2 therapy. The current status of this study is unclear, and it plans to enroll 20 participants.

Study design
This interventional study plans to enroll 20 women. The phase of the study is not specified.
What's involved
You would undergo a 12-lead echocardiogram procedure. The study measures outcomes at the end of therapy, approximately 457 days.
Compensation
Not stated in the trial record.
Follow-up
The study measures outcomes at the end of therapy, approximately 457 days.

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NCT07630402

Optimization of Cardiac Imaging in Women With Early-Stage Breast Cancer

Recruiting
NAAges 18–79Interventional
University of Rochester
~20 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:Echocardiogram

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Total Number of imaging tests
Measured over At the end of therapy, approximately 457 days
+1 more outcome measured
Breast Cancer With Low to Intermediate HER2 Expression
1 sites across 1 states
New York1

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Eligibility criteria

Inclusion

Female sex, age 18-79 years.
Histologically confirmed HER2-positive BC scheduled for ≈12 months of adjuvant HER2-TT
Baseline LVEF ≥ 55 % by 2-D echocardiography.
Ability to provide informed consent.

Exclusion

Prior HF, myocardial infarction, or cardiomyopathy.
Atrial fibrillation or significant valvular heart disease.
Cumulative anthracycline dose ≥ 250 mg/m².
Pregnancy or lactation.
Inability to comply with study procedures.
  • Total Number of imaging testsAt the end of therapy, approximately 457 days
  • Time to completion of HER 2 (human epidermal growth factor receptor 2) target therapy in daysend of therapy, approximately 457 days