Patient Navigation for Young Adult Childhood Cancer Survivors

This study is for young adults, aged 20-29, who had cancer as children and are now transitioning from pediatric to adult-focused healthcare. It aims to see if a program called "Navigation" can help more survivors successfully make this transition compared to standard care. Researchers want to know if Navigation increases the number of people who successfully transition and reduces unmet health-related social needs (HRSN). They will also look at how factors like gender, race, insurance, and quality of life might affect how well Navigation works. You would be compared to others receiving standard care.

Study design
This is an interventional study planning to enroll 190 participants. It compares a "Navigation" intervention to standard of care.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for their transition to adult-focused survivorship care within 18 months following study enrollment.

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NCT07630831

Patient Navigation for Improving Transition Success Among Multiply Disadvantaged Young Adult Survivors of Childhood Cancer

Not Yet Recruiting
NAAges 20–29InterventionalTreatment
Children's Hospital Los Angeles
~190 participants
Updated 2026-09-03 on ClinicalTrials.gov
What's tested:NavigationControl

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of participants with Transition to Adult-Focused Survivorship Care
Measured over Within 18 months following transition "launch" (study enrollment/baseline)
Cancer Childhood
1 sites across 1 states
California1
  • David Freyer, DO, MS · PRINCIPAL_INVESTIGATOR · Children's Hospital Los Angeles
  • Kimberly Miller, PhD · PRINCIPAL_INVESTIGATOR · Children's Hospital Los Angeles

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Eligibility criteria

Inclusion

diagnosed between the ages of 0-19 years with cancer or with any condition treated with cancer-like therapy.
currently in follow up at survivorship clinic or had a survivorship launch visit during the 12 months prior to study activation.
current age 20-29 (\>95% of patients will be age 20-21)
meet LIFE Clinic transition readiness criteria, as clinically applied:
at least 5 years off treatment
medically stable
demonstrate a workable understanding of transition
have an identified primary care provider
able to speak and read English or Spanish
can provide informed consent.

Exclusion

do not meet transition criteria
speak a language other than English or Spanish
are significantly impaired and cannot provide informed consent.
  • Proportion of participants with Transition to Adult-Focused Survivorship CareWithin 18 months following transition "launch" (study enrollment/baseline)

    The proportion of participants who complete a qualifying adult-focused survivorship care visit, defined as: For higher-risk survivors: a visit to the designated adult survivorship clinic For lower-risk survivors: a visit to a primary care provider that includes discussion of cancer history and/or late effects Transition success is: Self-reported by participants and Validated by study staff through contact with the receiving provider Participants without a cancer-focused component to the visit (e.g., urgent care, vaccination-only visits) will not be considered successful transitions. The outcome will be analyzed as a binary proportion (success vs. no success).