NCT07632248

A Study Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")

Not Yet Recruiting
NAAges 15–25InterventionalTreatment
Duke University
~128 participants
Updated 2026-06-08 on ClinicalTrials.gov
What's tested:FlexEDEducational Control

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline in the Body Image - Acceptance and Action Questionnaire (BI-AAQ)
Measured over Baseline, 4, 8, 12, 24, 36, 48 weeks
+8 more outcomes measured
Eating Disorders
Body Image
1 sites across 1 states
North Carolina1

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Female between the age of 15-25 years old.
Weight Concerns Scale score of \>=47.
Endorses one or more eating disorder behaviors (e.g., extreme dieting or exercise, subjective or objective binge eating, purging behaviors).

Exclusion

Currently meets the DSM-5 diagnostic criteria for full threshold anorexia nervosa, bulimia nervosa or binge eating disorder, or for an eating or feeding disorder that does not include body-image or weight related distress and is not the focus of study (e.g., ARFID, PICA) or a past diagnosis of one of these disorders.
Change in psychotropic medications in the past month.
Active suicidal ideation, current substance use disorder or diagnosed psychotic disorder.
Bipolar disorder not being treated with medication.
Currently in treatment for an eating disorder.
Non-English speaking.
  • Change from Baseline in the Body Image - Acceptance and Action Questionnaire (BI-AAQ)Baseline, 4, 8, 12, 24, 36, 48 weeks

    Self-report measure of body-image psychological flexibility. The measure consists of 13 (full measure) or 5 (short measure) items that ask about the degree to which thoughts and feelings about the body interfere with living. Higher scores indicate greater flexibility/adaptability.

  • Change from Baseline in the Body-Image Stroop Bias ScoreBaseline, 8 weeks, 24 weeks

    Change in reaction time to body-related versus neutral words in an emotional stroop paradigm. In this paradigm, participants identify the color of the written word as quickly as possible. Differences in reaction time between emotionally relevant words and neutral words is calculated as a bias score. Lower bias scores indicate improvement.

  • Change from Baseline in Eye Gaze Fixations - Body-Image Related ImagesBaseline, 8 weeks, 24 weeks

    Change in the number of fixations on body-image related images, including idealized bodies, overweight bodies, body-weight measurement, and images of binge eating and body-related distress. Fewer fixations indicate improvement.

  • Acceptability of the intervention8 weeks

    Enrollment targets met, \>70% of participants that start the intervention will complete \>80%, \>70% of participants and sessions will have user inputs indicating engagement.

  • Change from Baseline in Eating Disorder Examination (EDE)Baseline, 12 weeks, 24 weeks

    Clinician-administered interview assessing eating disorder symptom severity, producing a Global score (main outcome) and 4 Subscale scores: Restraint, Eating Concerns, Weight Concerns, Shape Concerns. Higher scores indicate greater symptomatology.

  • Change from Baseline in the Eating Disorder Examination - Questionnaire (EDE-Q)Baseline, 12, 24, 36, 48 weeks

    Questionnaire format of the clinician-administered interview assessing eating disorder symptom severity, producing a Global score (main outcome) and 4 Subscale scores: Restraint, Eating Concerns, Weight Concerns, Shape Concerns. Higher scores indicate greater symptomatology.

  • Change from Baseline in the Clinical Impairment Assessment (CIA)Baseline, 12, 24, 36, 48 weeks

    Measures the extent to which eating disorder symptoms impair functioning. Higher scores indicate greater impairment.

  • Change from Baseline in the Comprehensive Assessment of Acceptance and Commitment Therapy Processes -10 (CompACT-10)Baseline, 4, 8, 12, 24, 36, 48 weeks

    A 10-item measure of psychological flexibility as a multidimensional construct with subscales of Openness, Awareness and Engagement. Higher scores indicate greater flexibility/adaptability.

  • Change from Baseline in Daily Levels of Body Image Distress and Psychological FlexibilityBaseline, 8 Weeks

    4 days of ecological momentary assessment of 1) distress/body-image distress 2) problematic behaviors to change body weight/shape, 3) general attempts to suppress/get rid of unwanted thoughts and feelings, 4) avoiding doing things because of concern about body, and 5) the ability to maintain adaptive distance and 6) orient to values. Scaled items are on a Likert Scale 1=Not at All to 6=Very Much. For items 1-4, higher scores are more problematic; For items 5-6, higher scores are more flexible adaptive.