NCT07637110
Dry Weight Reduction Intervention Via Extra Ultrafiltration
Not Yet Recruiting
NAAges 18+InterventionalTreatmentUniversity of WashingtonInvestigator-initiated
~120 participants
Updated 2026-06-09 on ClinicalTrials.gov
What's tested:Ultrafiltration
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
24-hour continuous ambulatory blood pressure
Measured over Measurement performed at baseline compared to measurement performed at 24 weeks.
+1 more outcome measured
Conditions
Where it's being run
1 sites across 1 statesWashington1
Study leadership
- Bryan Kestenbaum, MD, MS · PRINCIPAL_INVESTIGATOR · University of Washington
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Receiving thrice weekly in-center hemodialysis treatments for end stage kidney disease for at least four weeks and clinical suspicion of volume excess based on either:
Exclusion
Age \<18 years
Receiving hemodialysis treatments for acute kidney injury
Receiving hemodialysis treatments for less than four weeks
Planned switch to peritoneal or home dialysis within next three months
Current or planned incremental hemodialysis (less than 3 treatments per week)
Current or planned intensive hemodialysis (four or more treatments per week)
Scheduled kidney transplantation
Major cardiovascular or bleeding event within previous 90 days
Receiving chemotherapy or radiation treatment for cancer
History of cirrhosis with ascites
Inability to complete 24-hour ambulatory blood pressure measurement
Wheelchair dependance or other inability to complete six-minute walk test
Pre-dialysis systolic blood pressure \<100 mmHg
Scheduled use of midodrine with hemodialysis treatments
History of non-adherence with dialysis treatments
Pregnancy
Institutionalized
Current or pending enrollment in hospice care
Inappropriate for enrollment based on investigator or nephrologist discretion
What this trial measures
- 24-hour continuous ambulatory blood pressureMeasurement performed at baseline compared to measurement performed at 24 weeks.
Blood pressure measured continously for a 24-hour period by wearing a blood pressure cuff on the upper arm.
- Symptoms of congestion.Questionnaire taken at Baseline compared the the questionnaire taken at 24 weeks.
Change in sypmtoms of congestion caused by fluid overload which we will access by using the Kidney-modified Kansas City Cardiomyopathy Questionnaire.