NCT07637396

Ankle-Brachial Index Changes Post Exercise and Its Effects on Patient-Centered Outcomes and Gait

Not Yet Recruiting
Not specifiedAges 18+Observational
Louisiana State University Health Sciences Center Shreveport
~85 participants
Updated 2026-06-09 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
magnitude of ABI reduction
Measured over immediately after exercise, at 1-, 3-, and 5-minute recovery intervals.
Peripheral Arterial Disease(PAD)
1 sites across 1 states
Louisiana1

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Eligibility criteria

Inclusion

individuals over 65 years of age
individuals aged 50-64 with a risk factor for atherosclerosis including diabetes mellitus, history of smoking, hyperlipidemia, hypertension, or family history of peripheral arterial disease (PAD)
individuals aged 18-50 with diabetes mellitus and one additional risk factor for atherosclerosis as noted above, or
individuals with known atherosclerotic disease in another vascular bed including the coronary, carotid, subclavian, renal, or mesenteric artery stenosis, and individuals with known PAD

Exclusion

contraindications to brachial and/or ankle pressure measurement including history of deep vein thrombosis
lymphedema of the arms or legs
history of mastectomy or current leg ulceration preventing placement of a blood pressure cuff around the lower leg
an inability to lie in a supine position for 15 min
self-reported inability to walk for 6 minutes
severe cardiac or pulmonary disease limiting exercise
inability to obtain a Dopplerable pulse
noncompressible arteries (ABI \>1.4)
those unable to consent
  • magnitude of ABI reductionimmediately after exercise, at 1-, 3-, and 5-minute recovery intervals.

    Measured as both absolute and percent change, calculated as the difference between baseline ABI and ABI immediately after exercise, at 1-, 3-, and 5-minute recovery intervals.