NCT07641413
Lung and Heart Function Across Decades of Life in Health
Recruiting
Not specifiedAges 24–68ObservationalUniversity of California, San FranciscoInvestigator-initiated
~200 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:Healthy control
At a glance
Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Normal reference values for heart and lung function within the age range relevant to the United States Veteran population.
Measured over 2 years
+2 more outcomes measured
Conditions
Where it's being run
1 sites across 1 statesCalifornia1
Study leadership
- Mehrdad Arjomandi, MD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Age 24-68
No respiratory complaints (defined as modified Medical Research Council score = 0)
No use of respiratory medications
Exclusion
Non-English speaking
Pregnancy
BMI\>35 Kg/m2
Tobacco smoking within prior year
Lifetime tobacco smoking of \>5 pack-years
Current inhaled cannabis use (any modality) \>2x weekly
Prior inhaled cannabis uses exceeding 2x weekly within the prior year
Illicit drug use (other than cannabis)
No prior or current major organ disease, including but not limited to:
Neuromuscular weakness
History of malignancy (other than non-melanoma skin cancer)-- HIV/AIDS
Autoimmune disease
Solid-organ or hematopoietic stem cell transplant
Cardiovascular disease (other than mild HTN; \< 140/90; controlled on 2 or less medications)
Poorly-controlled HTN (SBP\>140 or DBP\>90 or use of more than 2 anti-hypertensive medications)
Any history of congestive heart failure (CHF, either HFpEF or HFrEF)
Any history of arrythmia (including atrial fibrillation)
What this trial measures
- Normal reference values for heart and lung function within the age range relevant to the United States Veteran population.2 years
Pulmonary Function Testing: The purpose of this test is to determine the participant's lungs' capacity.
- Normal reference values for heart and lung function within the age range relevant to the United States Veteran population.2 years
Cardiopulmonary Exercise Testing: The purpose of this test is to determine the participant's lung and heart capacity during maximum exercise.
- Normal reference values for heart and lung function within the age range relevant to the United States Veteran population.2 years
Echocardiogram: The purpose of this test is to determine how well the subject's heart is functioning and identify causes of cardiac-related symptoms.