NCT07645820

Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares

Recruiting
Not specifiedAges 12–89Observational
Castle Biosciences Incorporated
~450 participants
Updated 2026-06-12 on ClinicalTrials.gov
What's tested:Nevisense electrical impedance spectroscopy

At a glance

Recruiting sites
4 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Relationship between skin measurements and subsequent atopic dermatitis flares
Measured over Measurements taken over 90 days, 5 days a week
+1 more outcome measured
Atopic Dermatitis
4 sites across 4 states
Arizona1
Nevada1
New Hampshire1
Texas1
Clare Johnson E VP Clinical Research
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Eligibility criteria

Inclusion

Are 12 to 89 years old.
Have been diagnosed with atopic dermatitis (eczema).
Have had at least one atopic dermatitis flare within the past 2 months.
Are willing and able to use the Nevisense Go device at home, complete an electronic symptom diary, and attend study visits.
If currently using systemic treatment for atopic dermatitis, have been on the same treatment for at least 3 months and do not plan to change treatment during the study.

Exclusion

Are unwilling or unable to avoid applying creams, lotions, ointments, or soap to measurement areas for 6 hours before measurements.
Do not have suitable skin areas for study measurements.
Have another skin condition that may affect study assessments.
Are pregnant.
  • Relationship between skin measurements and subsequent atopic dermatitis flaresMeasurements taken over 90 days, 5 days a week

    Electrical Impedance Spectroscopy (EIS) measurements collected over time to assess their relationship to subsequent participant-reported atopic dermatitis flares occurring before visible signs or symptoms are apparent.

  • Develop and validate an algorithm using Nevisense Go EISFrom enrollment until end of treatment at 90 days.

    To develop and validate an algorithm using Nevisense Go EIS data that can calculate the momentary likelihood of AD flares, before signs or symptoms