NCT07645924

A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

Recruiting
PHASE3Ages 18–75InterventionalTreatment
Kallyope Inc.
~1,800 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:ElismetrepPlacebo

At a glance

Recruiting sites
82 of 115 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pain freedom at 2 hours post-dose
Measured over Two hours post-dose
+1 more outcome measured
Migraine
115 sites across 35 states
California18
Texas10
Nevada7
New York7
Utah6
Missouri5
North Carolina5
Pennsylvania5

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Eligibility criteria

Exclusion

3 months prior to screening.
  • Pain freedom at 2 hours post-doseTwo hours post-dose

    Percentage of participants that report no pain at 2 hours post-dose. Pain will be measured on a 4-point Likert scale (0=none, 1=mild, 2=moderate, 3=severe).

  • Freedom from most bothersome symptoms (MBS) at 2 hours post-doseTwo hours post-dose

    Percentage of participants that report absence of their MBS (nausea, phonophobia, or photophobia) at 2 hours post-dose. MBS will be measured using a binary scale (0=absent, 1=present).