NCT07647939
Exclusion of Left Atrial Appendage Thrombus in Emergency Department Patients With Atrial Fibrillation Undergoing CT to Assess for Pulmonary Embolus: A Feasibility Study
Not Yet Recruiting
NAAges 18+InterventionalDiagnosticNorthwell HealthInvestigator-initiated
~60 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:Delayed Un-gated CT Scan for Left Atrial Appendage ThrombusDelayed Gated CT Scan for Left Atrial Appendage Thrombus
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of Indeterminate Left Atrial Appendage (LAA) Thrombus Scans
Measured over The overall assessment and statistical analysis of this primary outcome for feasibility determination will be conducted at the study completion, an average of one year.
Conditions
Where it's being run
1 sites across 1 statesNew York1
Who to contact
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Eligibility criteria
Inclusion
Patients above 18 years of age years deemed candidates for CT angiography for pulmonary embolism by the primary team on clinical grounds and noted to be in atrial fibrillation at the time.
Room air oxygen saturation above 92%
Systolic blood pressure above 100 mm Hg
Respiratory rate less than 24 breaths/min
Exclusion
Inability to personally give informed consent
Pregnant or breastfeeding individuals
Stroke like symptoms
ECG criteria for ischemia or infarction
Heart rate \<40 or \> 120 bpm (inclusive) or 3rd degree heart block
Unable to lie flat for at least 10 minutes
Unable to follow simple commands
Northwell Health Employees.
Non-English-speaking patients
What this trial measures
- Percentage of Indeterminate Left Atrial Appendage (LAA) Thrombus ScansThe overall assessment and statistical analysis of this primary outcome for feasibility determination will be conducted at the study completion, an average of one year.
The primary endpoint of this study is to test the hypothesis that less than or equal to 20% of the repeat CT scan (described above) will be indeterminate for the presence or absence of left atrial appendage thrombus. Additionally, the proportion of indeterminate gated CT scans will be compared to the proportion of indeterminate ungated CT scans.