NCT07648407
Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation
Not Yet Recruiting
NAAges 60+InterventionalPreventionVA Office of Research and DevelopmentGovernment-funded
~96 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:MicroneedlingTrichloroacetic acid peel
At a glance
Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change From Baseline in the Number of Actinic Keratosis due to treatment.
Measured over up to 4 years
+1 more outcome measured
Conditions
Where it's being run
2 sites across 2 statesIndiana1
Ohio1
Study leadership
- Matthew J Turner, MD · PRINCIPAL_INVESTIGATOR · Richard L. Roudebush VA Medical Center, Indianapolis, IN
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Adult Males and Females age 60 and older with 5 or more AKs on each forearm
Skin type fair-Fitzpatrick I-II
Able to comprehend procedures and risks
Exclusion
More than 10 AKs on an extremity, or AKs that are large (2-3+)
Medical history of Diabetes
Coagulopathy or easy bleeding
History of poor wound healing or scarring
Large tattoos that can interfere with study
Other serious health issues and other skin diseases that could interfere with the study
Recent (within 1 year) field therapies such as Efudex cream or PDT to forearms
Planning to leave region in next 4 years
What this trial measures
- Change From Baseline in the Number of Actinic Keratosis due to treatment.up to 4 years
Investigator will assess the number of actinic keratosis on both forearms
- Change From Baseline in the Number Non-Melanoma Skin Cancers due to treatment.up to 4 years
Investigator will assess the number of nonmelanoma skin cancers on both forearms.