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NCT07648407

Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation

Not Yet Recruiting
NAAges 60+InterventionalPrevention
VA Office of Research and Development
~96 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:MicroneedlingTrichloroacetic acid peel

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change From Baseline in the Number of Actinic Keratosis due to treatment.
Measured over up to 4 years
+1 more outcome measured

Conditions

Nonmelanoma Skin Cancer
Actinic Keratosis

Explore related trials

Actinic KeratosisSkin Carcinoma

NCT07648407

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Dayton VA Medical Center, Dayton, OH

    Dayton, Ohiostudy coordinator listed

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN

    Indianapolis, Indianastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Matthew J Turner, MD · PRINCIPAL_INVESTIGATOR · Richard L. Roudebush VA Medical Center, Indianapolis, IN

Who to contact

Matthew J Turner, MD
[email protected]
(317) 988-5000
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Adult Males and Females age 60 and older with 5 or more AKs on each forearm
Skin type fair-Fitzpatrick I-II
Able to comprehend procedures and risks

Exclusion

More than 10 AKs on an extremity, or AKs that are large (2-3+)
Medical history of Diabetes
Coagulopathy or easy bleeding
History of poor wound healing or scarring
Large tattoos that can interfere with study
Other serious health issues and other skin diseases that could interfere with the study
Recent (within 1 year) field therapies such as Efudex cream or PDT to forearms
Planning to leave region in next 4 years

What this trial measures

  • Change From Baseline in the Number of Actinic Keratosis due to treatment.up to 4 years

    Investigator will assess the number of actinic keratosis on both forearms

  • Change From Baseline in the Number Non-Melanoma Skin Cancers due to treatment.up to 4 years

    Investigator will assess the number of nonmelanoma skin cancers on both forearms.