Back to search results
NCT07649005

Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults

Recruiting
NAAges 55–75InterventionalPrevention
Florida State University
~30 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:low sodium/low potassium diethigh sodium/low potassium diethigh sodium/high potassium diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Endothelial function
Measured over "Day 11" after each of the three 10-day dietary interventions
+2 more outcomes measured

Conditions

Healthy Older Adults

Explore related trials

Healthy Older Adults

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Andrea Lobene · PRINCIPAL_INVESTIGATOR · Florida State University

Who to contact

Andrea Lobene
[email protected]
850-644-1829
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Adults ages 55-75 years
At least one-year post-menopause (females)
Willing and able to attend laboratory visits

Exclusion

BMI ≥35 kg/m2
Seated blood pressure \>135/85 mmHg
Current diagnosis or history of cardiovascular disease, diabetes, renal disease, cancer, or major cardiovascular event (e.g. heart attack or stroke)
Taking exogenous hormones or hormone replacement therapy
Following a vegan or gluten free diet
Significant weight loss (\>10% of body weight) in the last 6 months, or actively trying to lose weight
Current or recent use of a diuretic (within the past 6 months) (e.g. spironolactone, eplerenone)
Current or recent use of a potassium binding medication (within the past 6 months)
Current use of blood pressure lowering medications (e.g. ACE inhibitors, calcium channel blockers, diuretics, vasodilators, beta blockers, AngII receptor blockers)
Current or recent use of the medication trimethoprim
Elevated blood lipids (LDL cholesterol ≥190 mg/dL)
Elevated serum potassium level (\>5.1 mmol/L)
Elevated BUN (\>22 mg/dL)
Elevated creatinine (\>1.2 mg/dL)
Low eGFR (\<90 mL/min/1.73 m²)
Current or recent use of tobacco, nicotine, or illicit drugs
Radical hysterectomy or oophorectomy (females)

What this trial measures

  • Endothelial function"Day 11" after each of the three 10-day dietary interventions

    Brachial artery flow-mediated dilation as measured in % dilation

  • Blood pressure"Day 11" after each of the three 10-day dietary interventions

    24-hour ambulatory blood pressure

  • Arterial stiffness"Day 11" after each of the three 10-day dietary interventions

    Carotid-femoral pulse wave velocity