Brain and Sensory Stimulation for Primary Progressive Aphasia
This study is looking at whether special types of brain and sensory stimulation can help people with primary progressive aphasia (PPA), a condition that affects language. Researchers want to see if transcranial alternating current stimulation (tACS), which uses gentle electrical currents, or multisensory stimulation (light and/or sound flickers) can improve verbal short-term memory (STM). You might be able to join if you are 45 or older, have a diagnosis of PPA or mild cognitive impairment (MCI) without problems with daily activities, and have had a recent cognitive exam. The study will compare active tACS to a sham (fake) tACS to see if the active treatment helps. It will also compare memory before and after multisensory stimulation. The goal is to see if these methods can improve language outcomes.
- Study design
- This is an interventional study planning to enroll 20 participants. It will compare active tACS to sham tACS, and pre-multisensory stimulation to post-stimulation performance.
- What's involved
- Changes in short-term memory will be monitored during and immediately after 20 minutes of tACS, and immediately after 20 minutes of multisensory stimulation.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Stimulating the Aging Brain Using Brain and Sensory Stimulation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Priyanka Shah-Basak, PhD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Changes in STM capacity assessed using a verbal STM taskChanges monitored over pre, during and immediately after 20 minutes of tACS
Improvement in STM capacity with in-phase tACS and worsening of STM capacity with anti-phase tACS compared to sham tACS
- Changes in STM capacity with multisensory stimulation using a verbal STM taskChanges monitored pre and immediately after 20 minutes of stimulation
Improvement in STM capacity post-stimulation compared to pre-stimulation