NCT07653243
Home-Based Lower-Extremity Heat Therapy for Walking Function in Peripheral Artery Disease
Not Yet Recruiting
NAAges 50+InterventionalTreatmentAquilo Sports, LLC
~40 participants
Updated 2026-06-17 on ClinicalTrials.gov
What's tested:Lower-Extremity Heat TherapySham Lower-Extremity Heat Therapy
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
6-minute walk distance
Measured over 12 weeks
Conditions
Where it's being run
1 sites across 1 statesIndiana1
Study leadership
- Raghu Motaganahalli, MD · PRINCIPAL_INVESTIGATOR · Indiana University
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Men and women older than 50 years of age
Resting ankle-brachial index (ABI) of \<0.9 but \>0.4 in at least one leg
Exclusion
Critical limb ischemia (ischemic rest pain or ischemia-related, non-healing wounds or tissue loss
Prior amputation
Exercise-limiting comorbidity
Recent (\<3 months) lower-extremity revascularization or orthopedic surgery
Use of walking aid other than a cane
Active treatment for cancer
Chronic kidney disease (eGFR \<30 by MDRD or Mayo or Cockcroft-Gault formula)
Class 2 or 3 obesity (BMI ≥ 35 kg/m2)
Unable to fit into water-circulating trousers
What this trial measures
- 6-minute walk distance12 weeks
Participants will receive standardized instructions and will be asked to walk the greatest distance possible by walking back and forth along a 100-ft corridor for 6 min. The primary outcome will be a change from baseline in the 6-minute walk distance over 12 weeks in the HT-treated group as compared to the sham treatment group.