Clareon TruPlus vs Tecnis Eyhance IOLs in Cataract Patients

This study is comparing two different types of intraocular lenses (IOLs) – the Clareon TruPlus and the Tecnis Eyhance – in people with cataracts. Cataracts are cloudy areas in the eye's lens that can make vision blurry. The study wants to see which lens provides better corrected distance vision (how well you see with glasses or contacts) three months after surgery. You might be able to join if you are an adult with cataracts in both eyes and are planning to have both lenses replaced. The study is currently observing participants, but its overall status is unclear.

Study design: This is an observational study that will compare two groups of participants. It is randomized, double-masked (meaning neither you nor the assessor will know which lens you received), and plans to enroll 70 people.
What's involved: You would have a visit before your surgery and then a follow-up assessment three months after your surgery.
Compensation: Not stated in the trial record.
Follow-up: Your vision will be assessed three months after your surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Clareon TruPlus vs Tecnis Eyhance IOLs in Cataract Patients

Not Yet Recruiting

Not specifiedAges 18+Observational

Gainesville Eye Associates

~70 participants

Updated 2026-06-18 on ClinicalTrials.gov

What's tested:Clareon TruPlusTecnis Eyhance

At a glance

Recruiting sites

0 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Binocular corrected distance visual acuity (CDVA)

Measured over 3 months postoperatively

Conditions

Cataract

Where it's being run

1 sites across 1 states

Georgia1

Study leadership

Clayton Blehm, MD · PRINCIPAL_INVESTIGATOR · North Georgia Eye Associates

Who to contact

Maryann Thomas

[email protected]

770-532-4444

Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Willing and able to understand and sign informed consent.

Adult patient diagnosed with age-related cataracts bilaterally.

Planned bilateral cataract removal and with bilateral implantation of the Clareon TruPlus IOL/Toric BLF (T3-T5) or Tecnis Eyhance IOL/Eyhance Toric (equivalent to T3-T5).

Best monocular corrected distance visual acuity expected to be 0.1 logMAR (Snellen 20/25) or better in both eyes postoperatively as determined by surgeon.

Residual astigmatism expected to be \<= 0.50 diopters in both eyes postoperatively as determined by surgeon (After using either toric IOL or arcuate incision with laser or manual LRI).

Normal ocular findings aside from cataract.

Exclusion

Moderate-severe corneal pathology, irregular astigmatism, preexisting macular disease and other retinal degenerative diseases expected to cause future vision loss, glaucoma, severe dry eye disease, nystagmus, strabismus, zonular laxity or dehiscence, pseudoexfoliation.

Previous history of any ocular surgery including corneal refractive surgery.

History of amblyopia or monofixation syndrome with poor stereoscopic vision.

Participants desiring monovision.

Any planned simultaneous/combined procedures at time of cataract surgery (e.g. MIGs).

Participation in another clinical study that could interfere with the results.

Any active ocular infection or inflammation.

What this trial measures

Binocular corrected distance visual acuity (CDVA)3 months postoperatively

Trialytics