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Multisensory Rehabilitation for Vision Loss After Cortical Damage

This study is exploring a treatment called Multisensory Rehabilitation for people who have lost vision in part of their visual field (hemianopia or quadrantanopia) due to damage to the brain's visual cortex. This condition often causes significant challenges for patients and their families. The Multisensory Rehabilitation involves 12 sessions where you'll be exposed to visual and auditory stimuli in your blind spot. Researchers want to see if this training can improve your vision and daily activities. To join, you need to be between 18 and 85 years old, have stable vision loss (hemianopia) for at least four weeks, and have a specific type of brain lesion. The study aims to enroll 30 participants. The study's success will be measured by changes in your NIH Stroke Scale score and Activity Inventory scores after six months.

Study design
This is an interventional study with a planned enrollment of 30 participants. The phase of the study is not specified.
What's involved
You would participate in 12 research sessions of Multisensory Rehabilitation. There will also be clinical visits at the beginning and end of the training period.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be measured at Month 6 after starting the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07659691

Multisensory Rehabilitation of Vision Loss After Cortical Damage

Not Yet Recruiting
NAAges 18–85InterventionalTreatment
Wake Forest University Health Sciences
~30 participants
Updated 2026-08-27 on ClinicalTrials.gov
What's tested:Multisensory Rehabilitation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in National Institutes of Health Stroke Scale (NIHSS) score
Measured over Month 6
+1 more outcome measured

Conditions

Cortical Blindness

Explore related trials

Homonymous hemianopia

Where it's being run

1 sites across 1 states
North Carolina1

Study leadership

  • Benjamin Rowland, PhD · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences

Who to contact

Kimberly Hawley, RN
[email protected]
3367164031
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients will be recruited from the local subject population hospitalized/seen by Ophthalmology, Neurosurgery, and Neurology at Atrium Health Wake Forest Baptist
diagnosis of stable homonymous hemianopia (\>4 weeks) with absence of hemineglect
a lesion encompassing at least primary visual cortex but sparing parietal cortex, to include lesions caused by an ischemic or hemorrhagic stroke or post-surgical changes due to an oncologic or non-oncologic tumor
normal or correctable auditory and cognitive function
willingness to participate in the three-month program
ability to perform visual discriminations in their intact field
life expectancy ≥12 months

Exclusion

diagnosis of an unstable homonymous hemianopia and/or with hemineglect,
Abnormal or uncorrectable auditory and cognitive function
unwillingness to participate in the program
inability to perform the visual testing in their intact field
life expectancy \< 12 months
Any other condition that would compromise their ability to complete the study.

What this trial measures

  • Change in National Institutes of Health Stroke Scale (NIHSS) scoreMonth 6

    The National Institutes of Health Stroke Scale (NIHSS) is a standardized, 15-item physical and mental examination used by healthcare providers to objectively quantify the severity of an acute stroke. Scores range from 0 (no neurological deficit) to 42 (severe impairment).

  • Change in Activity Inventory scoresMonth 6

    A questionnaire that asks how vision affects everyday activities. It helps show which daily tasks are most important to the participant and how difficult those tasks may be because of vision problems. Patients rate the importance of a goal and the difficulty of tasks, resulting in an individually tailored dataset. This adaptive approach provides a comprehensive profile of how visual limitations affect everyday life.