Goji Berry and Vasomotor Symptoms Pilot Study

This study is looking at whether two different forms of goji berry powder can help women aged 40-65 who are experiencing frequent hot flashes (vasomotor symptoms). You would consume either Goji Berry Juice Powder or Goji Berry Powder daily as a mug cake for one month. Researchers want to see which form might be better at improving HDL cholesterol function, which is linked to heart health. They also want to see if these changes are connected to how often you have hot flashes and your thinking abilities. This is a small pilot study to help plan a larger study in the future. The study is currently unclear about its status and plans to enroll 6 women.

Study design
This is an interventional pilot study comparing two different goji berry powder formulations in a small group of 6 women.
What's involved
You would consume one mug cake daily for 30 days and track your hot flashes daily on a smartphone. The primary endpoint is measured at 1 month.
Compensation
Not stated in the trial record.
Follow-up
Your HDL cholesterol function will be measured at 1 month after starting the intervention.

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NCT07660315

Goji Berry and Vasomotor Symptoms Pilot Study

Not Yet Recruiting
NAAges 40–65InterventionalBasic science
University of California, Davis
~6 participants
Updated 2026-08-18 on ClinicalTrials.gov
What's tested:Goji Berry Juice PowderGoji Berry Powder

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
High-Density Lipoprotein (HDL) Cholesterol Efflux Capacity (CEC)
Measured over 1 month
Vasomotor Symptoms
1 sites across 1 states
California1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adult women aged 40-65 years
Peri- or postmenopausal with vasomotor symptoms (hot flashes) occurring ≥4 days/week over the past 2 weeks
Willing to consume one mug-cake daily for 30 days
Willing to complete daily VMS symptom tracking on a smartphone
Hormone therapy (HRT) is allowed if the dose has been stable for ≥8 weeks and hot flashes are still present

Exclusion

Combined intake of \>5 servings of eggs or lutein/zeaxanthin-rich vegetables per week
Current pregnancy or breastfeeding
Known allergy or intolerance to goji (Lycium barbarum) or to key mug-cake ingredients (e.g., wheat/gluten, dairy, and eggs)
Current use of warfarin (goji has reported interactions with anticoagulants); other anticoagulants will be reviewed case-by-case
Uncontrolled thyroid disease or other medical conditions likely to confound VMS assessment
Initiation or planned change of HRT, GLP-1 agonists, or other medications known to affect lipid metabolism or VMS during the 30-day study
Current participation in another interventional study
Any condition that, in the judgment of investigators, makes participation unsafe or data interpretation unreliable
  • High-Density Lipoprotein (HDL) Cholesterol Efflux Capacity (CEC)1 month

    Measure the capacity of isolated HDL to efflux cholesterol out of macrophages