Study of BHV-1300 for Graves' Disease
This study is looking at a drug called BHV-1300 to see if it is safe and effective for adults with Graves' disease. Graves' disease is an autoimmune condition that causes an overactive thyroid (hyperthyroidism). You might be able to join if you are between 18 and 70 years old, have Graves' disease confirmed by blood tests, and are currently experiencing hyperthyroidism. You cannot join if your hyperthyroidism is caused by something other than Graves' disease. Participants will receive either BHV-1300 or a placebo (an inactive substance), both given by injection under the skin. The main goal is to see how many people taking BHV-1300, compared to placebo, have normal thyroid function and are no longer taking other thyroid medications after 26 weeks. The current status of this study is unclear, but it plans to enroll 300 participants.
- Study design
- This is an interventional study comparing BHV-1300 to a placebo in 300 adult participants with Graves' disease.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome is measured at Week 26, indicating participants will be followed for at least that long.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
At a glance
Conditions
NCT07661056
Where you'd take part
This study runs at 50 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Site-004
Kansas City, Missourino site contact published
Recruiting
Site-006
San Diego, Californiano site contact published
Recruiting
Site-008
Canton, Ohiono site contact published
Recruiting
Site-009
Weslaco, Texasno site contact published
Recruiting
Site-010
North Charleston, South Carolinano site contact published
Recruiting
Site-011
Greenville, North Carolinano site contact published
Recruiting
Site-013
Layton, Utahno site contact published
Recruiting
Site-015
St Louis, Missourino site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of participants on BHV-1300 vs placebo who are not on an antithyroid drug and with normal thyroid function (total T3, free T4 (FT4), & TSH within normal limits) at Week 26.Week 26