Sleep Monitoring for Stellate Ganglion Block in PTSD Treatment

This study is looking at how a treatment called Stellate Ganglion Block (SGB) affects sleep in U.S. active duty service members and veterans who are also receiving Prolonged Exposure (PE) therapy for Post-Traumatic Stress Disorder (PTSD). SGB involves an injection of either ropivacaine (active) or saline (sham) near a cluster of nerves in the neck. You would wear a special headband called a Sleep Profiler for three nights before the injection and three nights after to measure your sleep patterns. Researchers will also ask you to complete questionnaires about your sleep. The goal is to see if SGB improves sleep, including total sleep time, how often you wake up, and your REM (Rapid Eye Movement) sleep, and if these sleep improvements help with PTSD. This study is for people aged 18 to 65 who are already participating in another related study (NCT05889741). About 40 people will be included.

Study design
This is an observational study involving about 40 participants. You must already be enrolled in a randomized clinical trial (NCT05889741) that compares active SGB with ropivacaine to sham SGB with saline.
What's involved
You would wear a Sleep Profiler headband for three nights before your SGB injection and for an additional three nights after. You will also complete self-report questionnaires about your sleep before and after the injection.
Compensation
Not stated in the trial record.
Follow-up
Sleep measurements and self-reports are taken around the time of the SGB injection (3 nights before and 3 nights after).

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NCT07667309

The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSD

Recruiting
Not specifiedAges 18–65Observational
The University of Texas Health Science Center at San Antonio
~40 participants
Updated 2026-06-25 on ClinicalTrials.gov
What's tested:Sleep Profiler Headband

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Total Sleep Time
Measured over Sleep onset to awakening time (approximately 8 hours)
+2 more outcomes measured
Post Traumatic Stress Disorder PTSD
2 sites across 1 states
Texas2
  • Kristi E Pruiksma, PhD, DBSM · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center at San Antonio

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  • Total Sleep TimeSleep onset to awakening time (approximately 8 hours)

    Time spent asleep from sleep onset to waking time

  • Wake time after sleep onsetSleep onset to awakening time (approximately 8 hours)

    Percentage of time spent awake after sleep onset

  • Rapid Eye Movement (REM) sleep stateSleep onset to awakening time (approximately 8 hours)

    Percentage of sleep time spent in REM