Study of Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

This study is testing a combination of three drugs – Gemcitabine, Mitomycin C, and Thalidomide – for people with advanced solid tumors (cancers that form in solid organs). You might be able to join if you are at least 18 years old, have a solid tumor that has spread or is advanced, and have already received some treatment. The study is looking to see how long people live without their cancer getting worse (Progression Free Survival) over 12 months. The current status of this study is unclear, but it plans to enroll up to 60 participants.

Study design
This is an open-label Phase II study, meaning both you and your doctors will know which treatments you are receiving. It plans to enroll 40-60 participants.
What's involved
You would receive Gemcitabine intravenously (into a vein) on days 1, 8, and 15, Mitomycin C intravenously every 6 weeks, and Thalidomide by mouth daily for 15 days. You would have CT scans or MRIs every 6 weeks for the first 6 months, and then every 12 weeks after that, for up to one year.
Compensation
Not stated in the trial record.
Follow-up
Your disease progression will be monitored for up to one year of treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07671534

Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

Recruiting
PHASE2Ages 18+InterventionalTreatment
Sarcoma Oncology Research Center, LLC
~60 participants
Updated 2026-06-26 on ClinicalTrials.gov
What's tested:GemcitabineMitomycin CThalidomide

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Progression Free Survival (PFS)
Measured over 12 months
Solid Tumor Cancer

NCT07671534

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Sarcoma Oncology Research Center / Cancer Center of Southern California

    Santa Monica, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Neal S. Chawla, MD · PRINCIPAL_INVESTIGATOR · Sarcoma Oncology Research Center, LLC

Opens a ready-to-send draft in your own email app — review before sending.

  • Progression Free Survival (PFS)12 months

    Progression free survival up to disease progression or death from any cause