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Period Pills for Menstrual Regulation Study

This study is looking at how acceptable and practical it is for people to use a combination of two medicines, mifepristone and misoprostol, to bring back a late period. This is called menstrual regulation. You might be able to join if you are 18 or older, read English, know your last period date, and your period is up to 21 days late. You also should not want to be pregnant and understand that if you are pregnant, these pills will end the pregnancy. The study wants to enroll 100 participants. Researchers will ask about your interest in using these "period pills" and your satisfaction with them after about 4 weeks.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll 100 participants.
What's involved
You will be given mifepristone and misoprostol. You will complete an enrollment survey and a follow-up survey 4 weeks after taking the medication.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 4 weeks after drug administration to assess satisfaction.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07671989

Period Pills for Menstrual Regulation: A New Reproductive Health Option

Recruiting
PHASE4Ages 18+Interventional
University of California, San Francisco
~100 participants
Updated 2026-06-26 on ClinicalTrials.gov
What's tested:Mifepristone + Misoprostol

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Interest in period pills
Measured over Documented at Enrollment Survey
+1 more outcome measured

Conditions

Menstrual Regulation
Menstrual Health Intervention

Explore related trials

Menstrual Health InterventionMenstrual Regulation

Where it's being run

2 sites across 2 states
California1
Virginia1

Study leadership

  • Ushma D Upadhyay, PhD, MPH · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

Who to contact

Ushma D Upadhyay, PhD, MPH
[email protected]
415-353-4626
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Be 18 years old or older
Read and speak English
Know the date of their last menstrual period within 2 days
Have a period that is late by up to 21 days
Must have had regular periods in the last 4 months
Does not want to be pregnant
Does not want to verify pregnancy status
Understand that if they are pregnant, the pills will end their pregnancy
Does not have contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

Exclusion

Under 18 years old
Does not read and speak English
Does not know the date of their last menstrual period within 2 days
Has not had regular periods in the last 4 months
Wants to be pregnant
Wants to verify pregnancy status
Does not display understanding that if they are pregnant, the pills will end their pregnancy
Has any contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

What this trial measures

  • Interest in period pillsDocumented at Enrollment Survey

    The proportion of the clinic-going population that may be interested in a period pill to bring on a late period and accept not having their pregnancy confirmed beforehand, therefore not knowing whether they terminated a pregnancy.

  • Satisfaction with period pillsDocumented at Follow-up Survey, 4 weeks after drug administration

    The proportion of participants reporting being "satisfied" or "very satisfied" with the period pills on a five-point Likert scale at follow-up (4 weeks).