Reducing Opioid Use After Total Hip Replacement

This study is looking at ways to manage pain after total hip replacement surgery while using fewer opioid pain medications. You could be eligible if you are an adult (18 or older) having a total hip replacement by a specific surgeon, and haven't used opioids chronically in the last three months. Participants will be randomly placed into one of two groups. One group gets the usual pain medication plan, with prescriptions sent to the pharmacy. The other group gets the same medications, but their opioid prescription (Tramadol) is a printed copy, meaning they decide if they want to fill it. The study will measure your pain and nausea levels, and how much opioid medication you use, up to three weeks after surgery.

Study design
This is an interventional study planning to enroll 100 participants. It compares two different approaches to pain management after total hip replacement.
What's involved
You will keep a pain journal and complete questionnaires about your medication intake for the first 21 days after surgery. You will also have follow-up visits over 3 months to assess your function and wellbeing.
Compensation
Not stated in the trial record.
Follow-up
Participants are followed for three months after surgery for function and wellbeing, and opioid consumption is tracked for three weeks post-op.

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NCT07672808

Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use

Not Yet Recruiting
NAAges 18+InterventionalTreatment
Henry Ford Health System
~100 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:Standard Multimodal Analgesic Regimen with Opioid PrescriptionOpioid-Reduced Multimodal Analgesic Regimen with Printed Prescription

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Postoperative Pain Score (Visual Analog Scale)
Measured over Preoperative baseline through 3 weeks postoperatively
+5 more outcomes measured
Arthroplasty, Replacement, Hip
1 sites across 1 states
Michigan1
  • Michael Charters, MD · PRINCIPAL_INVESTIGATOR · Henry Ford Health System

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Eligibility criteria

Inclusion

Adult patients age 18 and older
Patients who have undergone total hip arthroplasty by a single, fellowship trained Orthopaedic Surgeon.

Exclusion

Patients with incomplete data in medical records
Chronic opioid use in the last 3 months
Ipsilateral joint surgery in the last year
Cannot tolerate oral medications
Swallowing difficulties
Intolerance to Tylenol, Celebrex, Robaxin, Neurontin, or Tramadol
History of Alcohol abuse
History of Drug abuse
History of Renal impairment
History of Peptic ulcer disease
History of GI bleeding
Illicit narcotic usage in past 6 months
Chronic liver disease
Chronic pain syndrome
  • Postoperative Pain Score (Visual Analog Scale)Preoperative baseline through 3 weeks postoperatively

    Pain severity measured using a visual analog scale (VAS) scored 0-10, where 0 represents no pain and 10 represents the worst possible pain. Scores collected preoperatively, daily during inpatient admission, daily for the first week post-discharge, then weekly for 2 additional weeks via patient pain journal and phone/text check-ins.

  • Postoperative Nausea Score (Visual Analog Scale)Preoperative baseline through 3 weeks postoperatively

    Nausea severity measured using a visual analog scale (VAS) scored 0-10, where 0 represents no nausea and 10 represents the worst possible nausea. Scores collected preoperatively, daily during inpatient admission, daily for the first week post-discharge, then weekly for 2 additional weeks via patient pain journal and phone/text check-ins.

  • Opioid ConsumptionThree weeks post-op

    Total opioid consumption measured in morphine milligram equivalents (MME) and by dose and quantity. Inpatient opioid use collected via electronic medical record and the Michigan Automated Prescription System (MAPS). Post-discharge opioid use recorded by the patient in a postoperative pain journal.

  • Antiemetic Consumptionthree weeks postoperatively

    Total antiemetic consumption recorded by dose and quantity. Inpatient use collected via electronic medical record; post-discharge use recorded by the patient in a postoperative pain journal.

  • Length of Hospital StayPerioperative/Periprocedural

    Total number of days from surgical admission to hospital discharge following primary total hip arthroplasty.

  • Episodes of NauseaThree weeks postoperatively

    Number of nausea episodes documented. Inpatient episodes collected via electronic medical record; post-discharge episodes recorded by the patient in a postoperative pain journal.