Observational Study on Heart Dysfunction in Muscular Dystrophy
This study is looking at heart problems (cardiomyopathy) in people with Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and carriers of these conditions. Heart problems are a major cause of death in these diseases, but doctors don't fully understand how they develop. This study aims to learn more about how heart dysfunction progresses and to find ways to predict who might be at higher risk for severe heart disease or death using heart MRI images. The goal is to create tools that can help doctors worldwide. You may be able to join if you have DMD, BMD, or are a carrier, confirmed by a muscle biopsy or genetic test. The study will track outcomes like mortality (death) over 10 years.
- Study design
- This is an observational study, meaning researchers will watch and collect information without giving any specific interventions. It plans to include 1000 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for mortality from the start of the study up to 10 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials
At a glance
Conditions
NCT07674758
Where you'd take part
This study runs at 9 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Children's Hospital of Richmond at VCU
Richmond, Virginiastudy coordinator listed
Recruiting
Children's National
Washington D.C., District of Columbiastudy coordinator listed
Recruiting
Duke Children's Hospital
Durham, North Carolinastudy coordinator listed
Recruiting
Lurie Children's
Chicago, Illinoisstudy coordinator listed
Recruiting
Nationwide Children's
Columbus, Ohiostudy coordinator listed
Recruiting
Riley Children's Hospital
Indianapolis, Indianastudy coordinator listed
Recruiting
Seattle Children's
Seattle, Washingtonstudy coordinator listed
Recruiting
UC Davis
Sacramento, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Mortalitybaseline to 10 years
Time from biomarker of interest to mortality