Atropine Eye Drops for Watery Eyes

This study is testing if low doses of atropine ophthalmic solution eye drops can help adults with excessive watery eyes (epiphora). Researchers want to see if the drops reduce how often you experience watery eyes and what side effects, if any, you might have. They are comparing two different strengths of atropine (0.005% and 0.01%) to find out which works best. You might be able to join if you are 18 or older, have watery eyes that require wiping at least twice a day, and have good vision in at least one eye. The study aims to enroll 18 participants, but its current recruitment status is unclear.

Study design
This is an interventional study comparing two strengths of atropine ophthalmic solution in 18 participants.
What's involved
You will use the eye drops for one week, attend two clinic visits for checkups and eye tests, and receive a follow-up phone call about two weeks after starting.
Compensation
Not stated in the trial record.
Follow-up
You will receive a follow-up phone call about two weeks after starting the treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07676981

Atropine Eye Drops for Watery Eyes (Excessive Tearing)

Recruiting
PHASE2Ages 18+InterventionalTreatment
Rehan Ahmed
~18 participants
Updated 2026-06-30 on ClinicalTrials.gov
What's tested:Atropine ophthalmic solution

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Munk Score Change
Measured over Time Frame: From enrollment to the end of treatment at 1 week
Epiphora
2 sites across 1 states
Texas2

Opens a ready-to-send draft in your own email app — review before sending.

  • Munk Score ChangeTime Frame: From enrollment to the end of treatment at 1 week

    Proportion of subjects achieving a clinically meaningful Munk responder response (reduction of ≥2 Munk grades from baseline to Visit 2)