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Automated Adaptive Deep Brain Stimulation for Parkinson's Disease

This study is looking at a new way to deliver Deep Brain Stimulation (DBS) for people with Parkinson's disease (PD). DBS is a surgical treatment that uses a device similar to a pacemaker to send electrical signals to specific areas of the brain. This study compares two types of stimulation using the Medtronic Percept Neurostimulator: "adaptive DBS," which automatically adjusts the stimulation throughout the day, and "constant DBS," which delivers a steady level of stimulation. The main goal is to see if adaptive DBS can reduce bothersome movement symptoms more effectively than constant DBS over about one year. You may be able to join if you are 25-75 years old, have Parkinson's disease, and already have a Percept DBS device implanted. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 40 participants. It compares two types of Deep Brain Stimulation using the Medtronic Percept device.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured through study completion, an average of 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07682311

Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator

Recruiting
NAAges 25–75InterventionalTreatment
University of California, San Francisco
~40 participants
Updated 2026-09-14 on ClinicalTrials.gov
What's tested:Medtronic Percept Deep Brain Stimulation (adaptive DBS)Medtronic Percept Deep Brain Stimulation (cDBS)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in number of bothersome movement symptoms on data-driven adaptive deep brain stimulation compared to open-loop deep brain stimulation
Measured over Through study completion, an average of 1 year.

Conditions

PD - Parkinson's Disease

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Parkinson Disease

NCT07682311

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of California San Francisco

    San Francisco, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Simon Little, MBBS,PhD · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

Who to contact

Research Coordinator
[email protected]
5175152739
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

What this trial measures

  • Change in number of bothersome movement symptoms on data-driven adaptive deep brain stimulation compared to open-loop deep brain stimulationThrough study completion, an average of 1 year.

    Troublesome movement symptoms will be detected using validated wearable devices along with participant self-reporting.