Contingency Management for Smoking Cessation

This study is testing a new way to help people quit smoking by encouraging them to use a medication called varenicline and participate in counseling. All participants will receive 12 weeks of varenicline and referrals to their state tobacco quitline. Some participants will also receive "Health Rewards" (Contingency Management), which means they could earn financial incentives for taking their medication and attending counseling sessions. We are looking for 40 adults, aged 18 or older, who live in Kansas, smoke at least one cigarette a day, and can read English and use a mobile phone for text messages. The main goal is to see if this approach is practical and acceptable, and to measure how many quitline calls are completed and how much varenicline is taken over 12 weeks. The study status is currently unclear.

Study design
This is a pilot interventional study with 40 participants. It is a randomized clinical trial, meaning participants will be assigned by chance to either the Health Rewards group or the Control group.
What's involved
Participants will receive 12 weeks of varenicline and referrals to a state tobacco quitline. The study will measure how many quitline calls are completed and how much varenicline is taken over 12 weeks.
Compensation
Participants in the Health Rewards group will receive financial incentives for taking medication and attending counseling sessions. Payments will be automated and dispensed daily using a reloadable debit card.
Follow-up
The study will measure outcomes at Week 3 and Week 12, focusing on the proportion of quitline calls completed and varenicline pills taken.

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NCT07685899

Contingency Management to Promote Smoking Cessation: A Pilot Randomized Clinical Trial

Not Yet Recruiting
NAAges 18+InterventionalTreatment
University of Kansas Medical Center
~40 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:Health RewardsControl

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility outcomes
Measured over Week 3 to 12
+2 more outcomes measured
Smoking Cessation
1 sites across 1 states
Kansas1

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Eligibility criteria

Inclusion

Smoked in the past 30 days
Smoke at least 1 cigarette per day when they smoke
≥ 18 years old
Kansas resident
Speak/read English
Access to a mobile phone
Mobile phone receives text messages
No varenicline contraindications (no acute renal impairment)
Have no significant co-morbidity (i.e., life-threatening illness, communication barriers or altered mental status)
Cognitively able to participate
Physically able to participate
Not pregnant/breastfeeding

Exclusion

Medically ineligible for varenicline
Patient on smoking cessation medication within 2 weeks of admission date
Patient already talked to quitline in the past 2 weeks.
Patients participating in other quit smoking program or research study
  • Feasibility outcomesWeek 3 to 12

    Feasibility endpoints include: (1) the proportion of eligible subjects who subsequently enroll; and (2) the proportion of enrolled subjects who complete the 3-week, 6-week, and 12-week assessments.

  • Proportion of quitline calls completedWeek 12

    Completion of the five quitline calls according to Kansas quitline reports

  • Proportion of varenicline pills takenWeek 12

    Varenicline intake over 12 weeks of treatment according to the smart pill dispenser counting