Evaluating How Well Different Types of Light-sensitive Cells in the Eye Contribute to Its Focusing Ability

This study is looking at how different colors affect your eye's ability to focus. You would view shapes on a screen that change color, and your eye's focusing ability will be measured using a special device called a wavefront sensor. The colors used are grayscale, L and S cone modulation only, and L and M cone modulation only. The study aims to understand how your eye focuses on different colors, which is important for clear vision. To join, you need to be between 18 and 35 years old with normal or corrected-to-normal vision (20/20 or better with glasses/contacts). The study is currently unclear on its recruitment status.

Study design
This is an interventional study planning to enroll 20 participants. It is not specified if it is randomized or blinded.
What's involved
You would participate in two sessions, each lasting about 1 hour, on separate days. You will need to bite a piece of dental clay to stabilize your head during measurements.
Compensation
Not stated in the trial record.
Follow-up
Measurements are taken during the two 1-hour sessions, with no follow-up specified after the second session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07691463

Evaluating How Well Different Types of Light-sensitive Cells in the Eye Contribute to Its Focusing Ability

Recruiting
NAUp to 35InterventionalBasic science
Rochester Institute of Technology
~20 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Color

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Accuracy of ocular accommodation
Measured over Because this is a basic science experiment, each measurement takes place at the same time as the intervention. There will be two sessions, each lasting approximately 1 hour, on separate days (day 1 and day 2).
+1 more outcome measured
Monochromatic
L- and S-cone Modulation Only
L- and M-cone Modulation Only
M and S-cone Modulation Only
1 sites across 1 states
New York1

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Eligibility criteria

Inclusion

Between 18-35 years of age
Normal or corrected-to-normal (glasses/contact lenses) vision.

Exclusion

Vision worse than 20/20 while wearing glasses / contact lenses.
Fragile or loose teeth (participants need to bite a piece of dental clay to stabilize their heads so that measurements can be taken from their eyes)
Current pregnancy (experiment requires sitting down without moving for stretches of time)
Heart disease
Personal/familial history of epilepsy
  • Accuracy of ocular accommodationBecause this is a basic science experiment, each measurement takes place at the same time as the intervention. There will be two sessions, each lasting approximately 1 hour, on separate days (day 1 and day 2).

    Ocular accommodation is the focusing response of the lens in the eye. When the stimulus viewed by the participant changes in distance, the eye automatically refocuses. The investigators measure this refocusing using a device called a wavefront sensor. The investigators are particularly interested in how accurate this refocusing is, which is measured in units of diopters.

  • Speed of ocular accommodationBecause this is a basic science experiment, each measurement takes place at the same time as the intervention. There will be two sessions, each lasting approximately 1 hour, on separate days (day 1 and day 2).

    The investigators are interested in how quickly the eye refocuses when a near object moves farther away. Typically, this process takes around 1 second, but it can take longer or shorter depending on the individual and on the object being viewed. By analyzing data collected by the wavefront sensor, the investigators will calculate how long it took for the eye to refocus during each measurement.