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Cognitive Training for Functioning in PTSD

This study is testing a new computer program called COGENT (Cognitive ENhancement Training) for people with Posttraumatic Stress Disorder (PTSD). COGENT is designed to improve your ability to manage information in your working memory, which may help with daily functioning and PTSD symptoms. Researchers want to see if COGENT helps Veterans recover better by reducing cognitive disability and PTSD symptoms. You might be able to join if you have a PTSD diagnosis, experience cognitive complaints, speak English, and are willing to attend study sessions. The study will measure changes in your daily functioning and cognitive abilities over time. The current recruitment status is unclear.

Study design
This study is an interventional study planning to enroll 176 participants. It compares COGENT to a sham training (ST) program.
What's involved
You would attend assessment and treatment sessions. The study measures outcomes at baseline, after 10 weeks of treatment, and at 3-month and 6-month follow-ups.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07693686

Cognitive Training for Functioning in PTSD

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~176 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:COGENT (Cognitive ENhancement Training)ST (Sham Training)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in World Health Organization Disability Assessment Schedule (WHODAS 2.0), cognitive domain
Measured over baseline, post (week 10), 3-month follow-up, 6-month follow-up

Conditions

Posttraumatic Stress Disorder

Explore related trials

Post-Traumatic Stress Disorder

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Jessica A Bomyea, PhD · PRINCIPAL_INVESTIGATOR · VA San Diego Healthcare System, San Diego, CA

Who to contact

Jessica A Bomyea, PhD
[email protected]
(858) 642-3720
Email the study team

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Eligibility criteria

Inclusion

diagnosis of PTSD
presence of subjective cognitive complaints
fluent in English
willing to attend assessment and treatment sessions

Exclusion

past year history of psychotic or bipolar I disorders
past year history of severe alcohol or substance use disorder
history of severe traumatic brain injury or other known neurological condition that may be associated with cognitive dysfunction
acute suicidality necessitating immediate clinical intervention (within past 3 months)
presence of circumstances that require imminent intervention prior to other treatment (e.g., current domestic abuse)
plans for medication changes within the study timeframe
current or planned evidence-based psychotherapy for PTSD within the study timeframe
plans for changes to other psychosocial therapy within the study timeframe
presence of life-threatening or unstable medical conditions

What this trial measures

  • Change in World Health Organization Disability Assessment Schedule (WHODAS 2.0), cognitive domainbaseline, post (week 10), 3-month follow-up, 6-month follow-up

    The WHODAS is a widely used, standardized tool designed to assess the level of disability experienced by individuals across various health conditions, including mental health disorders like PTSD. The WHODAS measures disability across six domains of functioning. The current project will utilize the cognition domain score to measure cognitive disability. A simple score for the WHODAS 2.0 ranges from 36-180 with higher scores indicating the degree of functional limitations.