Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials

This study is looking at how well integrating Palliative Care Consultation (PPC) works for children and young adults (ages 0-25) with cancer who are considering joining a Phase 1 clinical trial. Phase 1 trials test new treatments mainly to see if they are safe. We want to see if having a specialized PPC doctor involved early on is practical and helpful for patients, their families, and their oncologists. The study aims to enroll 30 participants and is currently unclear about its recruitment status. Success will be measured by how feasible (practical) and acceptable this approach is over two years.

Study design
This is a single-arm study, meaning all participants will receive the same intervention. It aims to enroll 30 participants.
What's involved
You would have a formal PPC consultation during the eligibility screening for the Phase 1 trial, followed by standard PPC visits every 2-4 weeks.
Compensation
Not stated in the trial record.
Follow-up
The study will assess feasibility and acceptability over two years.

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NCT07696065

Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials

Recruiting
EARLY_PHASE1Ages 0–25InterventionalSupportive care
Phoenix Children's Hospital
~30 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:Pediatric Palliative Care Consultation

At a glance

Recruiting sites
1 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility
Measured over 2 years
+1 more outcome measured
Quality of Life Outcomes
3 sites across 3 states
Arizona1
Maryland1
Tennessee1

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Eligibility criteria

Inclusion

Patients (aged 0-25 years) diagnosed with cancer and undergoing evaluation for enrollment in a phase 1 trial, their caregivers, as well as their primary treating oncologist are eligible for study participation.

Exclusion

Previous palliative care exposure
  • Feasibility2 years

    Feasibility will be defined as a mean FIM score of ≥ 3 (coded 1-5) for \> 50% of caregivers and oncology providers; enrollment: ≥ 70% of eligible patients/caregivers will assent/consent; adherence: ≥ 75% of enrolled participants will complete all PPC study assessments as planned. Themes identified from qualitative findings, specifically from caregivers/patients' experiences with the PC team (either positive or negative) will be compared alongside quantitative data in a matrix to assess for overlap or variances in findings related to intervention feasibility, acceptability, and impact.

  • Acceptabilitytwo years

    Acceptability will be defined as a mean AIM score of ≥ 3 (coded 1-5) for \> 70% of caregivers and oncology providers. Themes identified from qualitative findings, specifically from caregivers/patients' experiences with the PC team (either positive or negative) will be compared alongside quantitative data in a matrix to assess for overlap or variances in findings related to intervention feasibility, acceptability, and impact.