Pilot Study on Exercise Regimens After Breast Cancer Treatment
This pilot study is looking at how different exercise programs affect "myokines" (proteins released by muscles during exercise) in women who have completed breast cancer treatment. You could participate if you are a woman between 20 and 89 years old, have been diagnosed with breast cancer (ductal carcinoma in situ or invasive carcinoma), and have received treatment like surgery, radiation, chemotherapy, immunotherapy, or hormonal therapy. The study is testing three types of exercise: Conditioning Resistance Training, Strength Resistance Training, and Hypertrophy Resistance Training. Researchers will measure myokine levels before and after exercise sessions to see how they change. The goal is to understand how exercise impacts these proteins after breast cancer treatment. The current status of this study is unclear.
- Study design
- This is an interventional pilot study with a planned enrollment of 21 women. It is not specified if the study is randomized or blinded.
- What's involved
- You would participate in one of three exercise regimens. Myokine production will be measured before and after exercise sessions over a four-week period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Myokine production will be measured immediately before and after the first exercise session, after the final exercise session of each week (weeks 1, 2, 3, and 4), and after the final exercise session of week 4 (end of the 4-week exercise regimen).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Colin Champ, MD · PRINCIPAL_INVESTIGATOR · AHN Radiation Oncology
Who to contact
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What this trial measures
- Change in Myokine Production After First Exercise SessionImmediately before and immediately after the first exercise session.
Quantification of a panel of 15 myokines (IL-5, IL-1ra, LIF, Irisin, SPARC, Decorin, Oncostatin M, Myostatin, Follistatin, Apelin, Fibroblast Growth Factor 21 (FGF21), Cathepsin-B, IL-15, METRNL, Myonectin) in both serum and tear samples. The change from pre-exercise to post-exercise levels will be determined.
- Change in Myokine Production After Final Exercise Session of Each WeekImmediately before and immediately after the final exercise session of weeks 1, 2, 3, and 4.
Quantification of a panel of 15 myokines (IL-5, IL-1ra, LIF, Irisin, SPARC, Decorin, Oncostatin M, Myostatin, Follistatin, Apelin, Fibroblast Growth Factor 21 (FGF21), Cathepsin-B, IL-15, METRNL, Myonectin) in both serum and tear samples for each group. The change from pre-exercise to post-exercise levels at the end of each week will be determined.
- Change in Myokine Production After Final Exercise Session of the Month (End of Study)Immediately before and immediately after the final exercise session of week 4 (end of the 4-week exercise regimen).
Quantification of a panel of 15 myokines (IL-5, IL-1ra, LIF, Irisin, SPARC, Decorin, Oncostatin M, Myostatin, Follistatin, Apelin, Fibroblast Growth Factor 21 (FGF21), Cathepsin-B, IL-15, METRNL, Myonectin) in both serum and tear samples for each group. The change from pre-exercise to post-exercise levels at the culmination of the 4-week exercise period will be determined.