A Study of Lung Cancer Risk in Never-Smokers

This study aims to understand what factors might increase the risk of lung cancer in people who have never smoked. Researchers will use a questionnaire and collect a blood sample for genetic analysis. The goal is to identify factors linked to non-small cell lung cancer (NSCLC) risk over three years. This information could help predict who might be more likely to develop lung cancer even without a smoking history. The study is looking for 500 participants, specifically women aged 40-74 who have smoked fewer than 100 cigarettes in their lifetime. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 500 participants. It is not specified if it is randomized or blinded.
What's involved
You would complete a questionnaire and have one vial of blood collected for genomic analysis during a regular treatment visit (if you have lung cancer) or a study-specific visit (if you don't).
Compensation
Not stated in the trial record.
Follow-up
The primary goal is to identify risk factors measured at 3 years, suggesting a follow-up period.

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NCT07701733

A Study of Lung Cancer Risk

Recruiting
Not specifiedAges 40–74Observational
Memorial Sloan Kettering Cancer Center
~500 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Questionnaire

At a glance

Recruiting sites
7 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Identify factors associated with the risk of NSCLC
Measured over 3 years
Lung Cancer
7 sites across 2 states
New York4
New Jersey3
  • Alexis Chidi, MD, PhD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

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  • Identify factors associated with the risk of NSCLC3 years

    analyses will include all participants who completed the demographic and exposure assessment and whole-exome sequencing