Mechanical Ventilator Adjustments and Patient Dyspnea Study
This study is looking at how changes to mechanical ventilator settings affect shortness of breath (dyspnea) in awake patients who need breathing support. Researchers will adjust your ventilator settings, such as tidal volume (the amount of air you breathe in and out), inspiratory flow (how fast air goes into your lungs), and PEEP (positive end-expiratory pressure, which keeps your airways open). They will also try different ventilator modes like VC/AC (volume control/assist control) and PSV (pressure support ventilation). After each change, you will be asked to rate your shortness of breath. The goal is to understand if these adjustments can make breathing more comfortable for patients on ventilators. This study is for patients aged 18 and older who are in the ICU, on a ventilator, awake, and able to communicate.
- Study design
- This is an interventional study with a planned enrollment of 20 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would have your ventilator settings adjusted for short periods (3 minutes per change). After each adjustment, you would rate your shortness of breath.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your dyspnea will be measured at 3 minutes after each change in ventilator settings.
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Mechanical Ventilator Adjustments and Patient Dyspnea
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Elias Baedorf-Kassis, MD · PRINCIPAL_INVESTIGATOR · Beth Israel Deaconess Medical Center
- Richard Schwartzstein, MD · STUDY_DIRECTOR · Beth Israel Deaconess Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in dyspnea scale from baseline3 minutes after the change
Change in dyspnea scale when changing the following settings Increase and decrease in tidal volume Increase, decrease in flow and change in flow curve Changes in PEEP Change to PSV to match their initial settings. We will use a modified multidimensional dyspnea scale, which includes from pleasant, neutral, slight sensation, annoying, distressing and unbearable. It also includes sensory qualities which ranges from 1 to 5 (5 being worse)