Back to search results

Comparing EMG Monitors for Deep Neuromuscular Blockade During Surgery

This study compares two devices, TetraGraph (Senzime) and TwitchView (Blink), that monitor how deeply your muscles are relaxed during surgery. This is important for procedures like laparoscopic (keyhole) or robotic abdominal surgery, or VATS (video-assisted thoracic surgery) where deep muscle relaxation is needed. Researchers want to see which device is better at detecting unwanted muscle movements or breathing efforts while you are under deep muscle relaxation. You could be eligible if you are an adult (18 or older) having one of these surgeries at The Ohio State University Wexner Medical Center, and your surgery is expected to last longer than 3 hours. The study is looking for 35 participants. The current recruitment status is unclear.

Study design
This study is an interventional trial comparing two monitoring devices in 35 participants. Each participant will have both devices placed on opposite arms during surgery.
What's involved
You would have both monitoring devices placed on your dominant hand during your elective surgery. Standard anesthesia care will be provided throughout the procedure.
Compensation
Not stated in the trial record.
Follow-up
Your muscle relaxation will be monitored throughout the surgical procedure, from the start of deep muscle relaxation until the end of surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07706504

Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery

Recruiting
NAAges 18+InterventionalDiagnostic
Ohio State University
~35 participants
Updated 2026-07-15 on ClinicalTrials.gov
What's tested:TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand)TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of intraoperative diaphragmatic movement during deep neuromuscular blockade
Measured over During maintenance of deep neuromuscular blockade throughout the surgical procedure, from achievement of deep neuromuscular blockade after induction of general anesthesia until completion of surgery prior to emergence.
+1 more outcome measured

Conditions

Neuromuscular Blockade

Explore related trials

Neuromuscular Blockade

Where it's being run

1 sites across 1 states
Ohio1

Who to contact

Alberto Uribe, MD
[email protected]
6142933559
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Adult male or female patients aged ≥ 18 years old.
Patients undergo elective abdominal laparoscopic/robotic or thoracic video-assisted (VAT) surgeries requiring general anesthesia for greater than 3 hours at The Ohio State University Wexner Medical Center.
Able to provide a signed, written informed consent.
Able to speak, read, and write in English.
ASA physical status I-III.

Exclusion

Patients who require emergency surgery or an emergent intervention.
Any documented cognitive or psychological disorders that, in the investigator's opinion, can interfere with the patient's pain perception.
Vulnerable populations: pregnant females, prisoners, breastfeeding.
Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study (patients with pre-existing neuromuscular diseases.
Allergy or contraindications to any of the anesthetics, NMB agents, or sugammadex.
Patients with anatomical abnormalities of the hands or arms that prevent proper placement of the sensors for nerve stimulation.
Limited access to the monitoring area due to surgical positioning.
Patients with peripheral vascular disease, since it may affect measurement accuracy.

What this trial measures

  • Incidence of intraoperative diaphragmatic movement during deep neuromuscular blockadeDuring maintenance of deep neuromuscular blockade throughout the surgical procedure, from achievement of deep neuromuscular blockade after induction of general anesthesia until completion of surgery prior to emergence.

    The number of spontaneous diaphragmatic movement events observed during maintenance of deep neuromuscular blockade will be recorded and compared between participants monitored with the TetraGraph (Senzime) and TwitchView (Blink) electromyography (EMG) neuromuscular monitoring devices.

  • Incidence of spontaneous breath-initiation efforts during deep neuromuscular blockadeDuring maintenance of deep neuromuscular blockade throughout the surgical procedure, from achievement of deep neuromuscular blockade after induction of general anesthesia until completion of surgery prior to emergence.

    The number of spontaneous breath-initiation efforts observed during maintenance of deep neuromuscular blockade will be recorded and compared between participants monitored with the TetraGraph (Senzime) and TwitchView (Blink) EMG neuromuscular monitoring devices.